<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
120 5327019 Switzerland 2003 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M   L10V, I13V, K14R, I15V, K20I, E35G, M36I, R41K, L63P, G68E, H69R, A71T, L89I  
>5327019| codons 1-99
PQITLWQRPVVTVRVGGQLIEALLDTGADDTVLEGINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICERKTIGTVLVGPTPVNIIGRNIMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       V35T, T39S, K102R, D121H, K122E, I135T, S162A, K173T, Q174R, D177E, I178M, G196R, T200A, Q207D, R211K  
>5327019| codons 29-224
EKIKALTEICSEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFW
EVQLGIPHPAGLKRKKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSTNNETPGIRYQYNV
LPQGWKGSPAIFQASMTKILEPFRTRNPEMVIYQYVDDLYVGSDLEIRQHRAKIEELRDH
LLKWGFTTPDKKHQKE

References
Author Title Citation
von Wyl, V Emergence of HIV-1 drug resistance in previously untreated patients initiating combination antiretroviral treatment: a comparison of different regimen types. Arch Intern Med, 2007