<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
110 5247133 Switzerland 2004 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 None NA
2 NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
N88S   L10I, I13V, K14R, G16E, K20I, E35Q, M36I, R41K, R57K, H69K, T74S, L89M  
>5247133| codons 1-99
PQITLWQRPIVTVRIEGQLIEALLDTGADDTVLEQINLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGKKAIGSVLVGPTPVNIIGRSMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39L, K43Q, K104R, K122E, D123S, S162A, K173A, Q174K, P176S, D177E, T200A, Q207E, R211K, F214L  
>5247133| codons 29-224
EKIKALTEICLEMEQEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFW
EVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNV
LPQGWKGSPAIFQASMTKILEPFRAKNSEIVIYQYMDDLYVGSDLEIGQHRAKIEELREH
LLKWGLTTPDKKHQKE

References
Author Title Citation
von Wyl, V Emergence of HIV-1 drug resistance in previously untreated patients initiating combination antiretroviral treatment: a comparison of different regimen types. Arch Intern Med, 2007