Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SWC-9877 | P9877-665 | U.S. | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 70 |
| 2 | AZT+ DDC | 36 |
| 3 | 3TC | 32 |
| 4 | 3TC+ DDI+ IDV | 38 |
| 5 | D4T+ SQV | 7 |
| 6 | DDC+ RTV+SQV | 7 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | L33F, G73S | L10I, E34K, N37D, I62V, L63P, V77I, I93L |
| >P9877-665| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVFKEMDLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKAISTVLIGPTPVNVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | V35I, T39S, R83K, I135T, S162D, E169D, D177E, I178L, I202V, E203K, Q207E, R211K |
| >P9877-665| codons 30-218 KIKALIEICSELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKKTQDFWE VQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSTNNETPGIRYQYNVL PQGWKGSPAIFQDSMTKILDPFRKQNPELVIYQYVDDLYVGSDLEIGQHRTKVKELREHL WKWGFYTPD |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |