Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4900 | CA12008 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 126 |
| 2 | 3TC+AZT | 100 |
| 3 | 3TC+AZT+IDV | 56 |
| 4 | D4T+DDI+EFV | 37 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R | K219Q | L100I, K103N | I50T, K122E, D123S, I135V, K166R, D177E, T200I, E203D, R211K, F214L, D218E, V245M, A272P, A304G |
| >CA12008| codons 1-304 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKTGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRIKIDELRQHLLKWGLTTPEQKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE LELG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | L10F | L33V, L63P, A71V |
| >CA12098| codons 1-99 PQITLWQRPFVTIKIGGQLKEALLDTGADDTVVEEMNLPGRWKPKMIGGIGGFVKVRQYD QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |