<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA1451 CA11803 U.S. 1999 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT+Unknown NA
2 3TC+D4T+IDV 47
3 D4T+DDI+NFV 32

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N L10F, N88D I15V, K20KT, E35D, M36V, R57K, L63P, I93L  
>CA11803| codons 1-99
PQITLWQRPFVTIKVGGQLTEALLDTGADNTVLEDVNLPGRWKPKMIGGIGGFIKVKQYD
QIPIEICGHKAIGTVLVGPTPVNIIGRDLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R, M184V T215V     E6D, K11R, K20R, K64R, T69N, R83K, A98S, K102KR, T200I, Q207D, K249R, A272P, K277R, T286A, I293IV, E297R  
>CA11657| codons 1-302
PISPIDTVPVRLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIRKKDSNRWRKLVDFRELNKKTQDFWEVQLGIPHPSGLKRKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRIKIEELRDHLLRWGFVTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPERDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVVPLTREAE
LE

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005