Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4787 | CA11680 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP+Unknown | 17 |
| 2 | Unknown | 79 |
| 3 | AZT+DDI+NFV | 45 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, T215F | K103N, Y181C | K122E, I135V, G196E, Q207A, V241M, V245Q |
| >CA11680| codons 1-255 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYMDDLYVGSDLEIEQHRTKIEELRAHLLRWGFFTPDKKHQKEPPFLWMGYELHPDKWT MQPIQLPEKDSWTVN |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88ND | K14R, I15V, E35D, M36MV, N37D, I62V, L63P, V77I, I93L |
| >CA11830| codons 1-99 PQITLWQRPLVTIRVGGQLKEALLDTGADNTVLEDVDLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKAIGTVLIGPTPVNIIGRDLLTQLGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |
| Melikian, GL | Standardized comparison of the relative impacts of HIV-1 reverse transcriptase (RT) mutations on nucleoside RT inhibitor susceptibility. | AAC, 2012 |