Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SWC-3714 | P3714-941 | U.S. | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ RTV | 18 |
| 2 | 3TC+ AZT+ IDV+ RTV | 39 |
| 3 | D4T+ DDC+ IDV+ SQV | 25 |
| 4 | DDI+ IDV+ NFV+ NVP | 14 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69D, L74LV, M184V, L210W, T215Y | F116Y | Y181I | E44D, E53G, K122E, I135V, S162C, I178M, T200A, Q207E, R211K | E42EA |
| >P3714-941| codons 30-236 KIKALVEICTELAKDGKISKIGPGNPYNTPVFAIKKKDSDKWRKVVDFRELNKRTQDFWE VQLGIPHPAGLKKKKSVTVLDVGDAYYSVPLDEDFRKYTAFTIPSVNNETPGIRYQYNVL PQGWKGSPAIFQCSMTKILEPFRKQNPDMVIIQYVDDLYVGSDLEIGQHRAKIEELREHL WKWGFYTPDKKHQKEPPFLWMGYELHP |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Gonzales, MJ | Protease and reverse transcriptase mutation patterns in HIV-1 isolates from heavily treated persons: comparison of isolates from northern California with isolates from other regions. | ARHR, 2003 |