Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SWC-2826 | P2826-1171 | U.S. | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ IDV | 20 |
| 2 | NFV+ NVP+ D4T | 27 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | G73S | L10LI, I13V, R41K, L63P, V77I |
| >P2826-1171| codons 1-92 PQITLWQRPIVTVKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIKVRQYD QIPIEICGHKAISTVLIGPTPVNIIGRNLMTQ |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, M184MV, T215F | K219Q | Y181I | A98G | I135T, I202V, D218E |
| >P2826-1171| codons 22-236 KQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELN KRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSTNNETPG IRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIIQYVDDLYVGSDLEIGQHRTK VEELRQHLLRWGFFTPEQKHQKEPPFLWMGYELHP |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Wu, TD | Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. | J Virol, 2003 |