Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SWC-3926 | P3926-148 | U.S. | 1996 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDC | 12 |
| 2 | 3TC+ AZT | 49 |
| 3 | 3TC+ AZT+ SQV | 22 |
| 4 | 3TC+ D4T+ IDV | 2 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69D, M184V, L210W, T215Y | K219R | E44D, V118I, S162C, R211K, L228R |
| >P3926-148| codons 31-236 IKALVEICTELEKDGKISKIGPENPYNTPVFAIKKKDSDKWRKLVDFRELNKRTQDFWEV QLGIPHPAGLKKKKSVTVLDVGDAYFSIPLDKDFRKYTAFTIPSINNETPGIRYQYNVLP QGWKGSPAIFQCSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKIEELRQHLW KWGFYTPDRKHQKEPPFRWMGYELHP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54V, V82A | L10I, I15V, Q18L, N37D, L63Q, A71T, I93X |
| >P3926-148| codons 1-93 PQITLWQRPIVTIKVGGLLKEALLDTGADDTVLEEMDLPGRWKPKMIVGIGGFVKVRQYD QIQIEICGHKTIGTVLVGPTPANIIGRNLLTQF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |