Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SWC-3636 | P3636-1388 | U.S. | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ NFV+ NVP | 6 |
| 2 | 3TC+ AZT+ RTV+ SQV | 27 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K103N | T39A, V118I, I135T, E138Q, S162C, G196E |
| >P3636-1388| codons 29-237 EKIKALVEICAELEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFW EVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPLDKDFRKYTAFTIPSTNNQTPGIRYQYNV LPQGWKGSPAIFQCSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIEQHRTKIEELRQH LWRWGFYTPDKKHQKEPPFLWMGYELHPD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14R, I15V, L19M, V77I |
| >P3636-1388| codons 1-99 PQITLWQRPLVTIRVGGQMKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILIEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |