Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SWC-1640 | P1640-1864 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP+ SQV | 8 |
| 2 | D4T+ NVP+ RTV+ SQV | 26 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | K103N, V106A | S162C, E169D, I178L, Q207E, R211K |
| >P1640-1864| codons 22-233 KQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELN KRTQDFWEVQLGIPHPAGLKKNKSATVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPG IRYQYNVLPQGWKGSPAIFQCSMTKILDPFRKQNPDLVIYQYMDDLYVGSDLEIGQHRTK IEELREHLWKWGFYTPDKKHQKEPPFLWMGYE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, G48V, I54V, V82T, I84V | K43R, I62V, L63P, I93L | A71NT |
| >P1640-1864| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWRPKIIVGIGGFVKVRQYD QVPIEICGHKNIGTVLVGPTPTNVIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |