Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1869 | CA11210 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+IDV | 72 |
| 2 | D4T+DLV+RTV+SQV | 9 |
| 3 | 3TC+AZT+IDV | 56 |
| 4 | D4T+EFV+NFV | 32 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74LV, T215Y | L100I, K103N | A98G | S3C, K20R, V35I, E44D, R83K, V111I, V118I, I142IV, K166R, I167V, T200A, I202V, E203ED, H208Y, L210S, R211K, H221Y, V245T, E248D, D250E, A272P, K277R | M16MI |
| >CA11210| codons 1-281 PICPIETVPVKLKPGIDGPRVKQWPLTEEKIKALIEICTELEKDGKISKIGPENPYNTPV FAIKKKNSTKWRKVVDFRELNKKTQDFWEVQLGIPHPGGIKKNKSVTVLDIGDAYFSIPL DKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTRVLEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRAKVDELRQYLSKWGFYTPDKKYQKEPPFLWMGYELHPDKWT VQPITLPDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCK |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, V82A | L24I | L10I, I15V, R41K, L63P, T74S |
| >CA11235| codons 1-99 PQITLWQRPIVTIKVGGQLKEALIDTGADDTVLEEMNLPGKWKPKLIGGIGGFIKVRQYD QIPIEICGHKAIGSVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | Extended spectrum of HIV-1 reverse transcriptase mutations in patients receiving multiple nucleoside analog inhibitors. | AIDS, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |