Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1624 | CA11023 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDC | 104 |
| 2 | 3TC+AZT+IDV | 26 |
| 3 | 3TC+AZT+RTV+SQV | 74 |
| 4 | D4T+DDI+RTV+SQV | 57 |
| 5 | ABC+D4T+EFV | 23 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V | L24I, L33F, F53L, G73C, N83D | I15V, E34Q, M36L, N37NS, L38W, P39PS, R57K, D60E, I62V, L63P, A71V |
| >CA11023| codons 1-99 PQITLWQRPLVTIKVGGQLKEALIDTGADDTVFQELSWSGRWKPKMIGGIGGLVKVKQYE QVPIEICGHKVICTVLVGPTPVDIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K219N | L100I, K103N | T39A, E44D, V118VI, K122KE, H208Y, R211K, V245T, K277R, R284K, T286A, V292I, E297K |
| >CA10933| codons 1-303 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKDGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQYLWKWGFYTPDNKHQKEPPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLKGAKALTEIIPLTKEAE LEL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |