Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4490 | CA10973 | U.S. | 1998 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+SQV | 14 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P4S, E28K, K32E, V35K, E36A, T39E, S48T, V60VI, V118I, K122E, D123N, I142M, K173A, Q174K, T200A, Q207E, R211K, F214L, T240TA, V245Q | F124FV, Y127YD |
| >CA10973| codons 1-256 PISSIETVPVKLKPGMDGPKVKQWPLTKEKIEALKAICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DENVRKDTAFTIPSINNETPGMRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWA VQPIQLPEKDSWTVND |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, K45KR, L63P, H69K, L89LM, I93L |
| >CA11062| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPRMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |