Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4325 | CA10725 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 74 |
| 2 | AZT+DDI | 22 |
| 3 | 3TC+AZT | 26 |
| 4 | 3TC+AZT+IDV | 96 |
| 5 | D4T+EFV+NFV | 61 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, V82T, N88S | L10I, L19S, I62V, L63P, A71V, I85V, I93L |
| >CA10725| codons 1-99 PQITLWQRPIVTIKIGGQSKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPIEICGHKVIGTVLVGPTPTNIVGRSLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, T215F | V75VI, K219E | L100LI, K103N | S68SG, K122E, D123S, I132IL, Y144X, K166R, I202V, R211RS, L228LR | A267AG |
| >CA10516| codons 1-268 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKNGTRWRKLIDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTLPSINNETPGIRXQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKVEELRQHLLSWGFFTPDEKHQKEPPFRWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWGS |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |