Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4305 | CA10697 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 218 |
| 2 | 3TC+AZT | 22 |
| 3 | 3TC+AZT+RTV | 61 |
| 4 | 3TC+AZT+NVP | 48 |
| 5 | D4T+DDC+NFV | 39 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | I13X, I15V, E35D, M36I, N37D, L63P, V75I |
| >CA10697| codons 1-99 PQITLWQRPLVTMKVGGQLKEALLDTGADNTVLEDIDLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTILVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| A62V | Y181YC, G190GA | T7A, K64R, T69S, D86X, K101KQ, K122E, I135V, Y144F, T200TA, E204D, T215X |
| >CA10494| codons 1-278 PISPIEAVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FVIRKKDSSKWRKLVDFRELNKRTQEFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGIRFQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYMDDLYVASDLEIGQHRAKIEDLRQHLLRWGFXTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQ |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |