Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1343 | CA10633 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 32 |
| 2 | None | 13 |
| 3 | DDI | 12 |
| 4 | AZT+DDC | 17 |
| 5 | None | 12 |
| 6 | D4T | 27 |
| 7 | 3TC+D4T | 31 |
| 8 | 3TC+D4T+IDV | 49 |
| 9 | 3TC+DDI+RTV | 17 |
| 10 | None | 10 |
| 11 | 3TC+D4T+RTV+SQV | 25 |
| 12 | D4T+DDI+EFV | 26 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | I31IL, K64KR, D86N, V90I, K101KQ, I135T, S162Y, V254I, A272P, T286A |
| >CA10633| codons 1-303 PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALVEICTEMEKEGKISKIGPENPYNTPV FAIRKKDSTKWRKLVDFRELNKRTQNFWEIQLGIPHPAGLQKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTINDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTEEAE LEL |
References
| Author | Title | Citation |
| Gonzales, MJ | Protease and reverse transcriptase mutation patterns in HIV-1 isolates from heavily treated persons: comparison of isolates from northern California with isolates from other regions. | ARHR, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |