Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1154 | CA10455 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI | NA |
| 2 | 3TC+ AZT+ SQV | 114 |
| 3 | 3TC+ D4T+ SQV | 67 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, K70R, M184V, T215FV | K219Q | E28EA, K43N, K122E, I135IT, D177DE, G196E, Q197K, D218E |
| >CA10455| codons 1-245 PISPIETVPVKLKPGMDGPKVKQWPLTAEKIKALVEICTELENEGKISKIGPENPYNTPV FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYVDDLYVGSDLEIEKHRTKIEELRQHLLRWGFFTPEQKHQKEPPFLWMGYELHPDKWT VQPIV |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54V, L90M | L10I, E21X, M36MI, I62IV, L63LP, I64V, A71V, I93L |
| >CA10663| codons 1-99 PQITLWQRPIVTIKIGGQLKXALLDTGADDTVLEEINLPGRWKPKMIVGIGGFVKVRQYD QVPVEICGHKVIGTVLVGPTPVNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |