<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt1 Pt1-W39 France 2007 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|RTI NA
2 3TC+ABC+AZT+DRV+ETR+RAL+T20 39

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
G140GS, Q148QH   E11D, A21T, A23AV, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D256DE, D278E L101LF
>Pt1-W39| codons 1-288
FLDGIDKAQEDHEKYHSNWRTMVSEFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFFLKLAGRWPVKTIHTDNGGN
FISTAVKAACWWAGIKQEFSIPYNPQSHGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQISKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQENSEIKVVPRRKAKIIRDYGKQMAGEDCVASRQDED

References
Author Title Citation
Charpentier, C Drug resistance profiles for the HIV integrase gene in patients failing raltegravir salvage therapy. HIV Med, 2008