Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A1424 | A1424_C1 | Mali | 2006 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K101E, G190A | K32E, V35T, E36A, T39K, K43E, K122E, D123S, I135R, I142V, S162Y, K173T, Q174K, D177E, V179I, Q197E, Q207A, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, E312D, I326V, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376V, T386A, K388R, A400T, T403M, W410Y, E432D, V435I |
| >A1424_C1| codons 1-440 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIEALTAICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSRNNETPGVRYQYNVLPQGWKGSPAIFQYSMTKILEPFRTKNPEIII YQYVDDLYVASDLEIGEHRTKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKDPVHGVYYDPSKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVRQLVEVVQKVVTESIVIWGKAPRFKLPIQKETWETWWMEYWQATYIPEWEFVNTP PLVKLWYQLEKDPIIGAETF |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, T12P, I13V, K14R, G16E, E35D, M36I, R41K, L63V, H69K, K70R, L89M |
| >A1424_C1| codons 1-99 PQITLWQRPVVPVRIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIVIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Sylla, M | Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. | Antivir Ther, 2008 |