Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A2536 | A2536_C1 | Mali | 2006 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219Q, N348I | K103N, Y188L | K11Q, V35T, T39L, K49R, K122E, D123N, S134R, I135V, S162A, E169Q, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, P243Q, V245Q, T286A, E291D, I293V, P294T, S322T, G335D, R356K, M357R, G359S, A371V, I375V, A376T, T377M, T386A, K390R, T403M, E432D | N136I, I159L |
| >A2536_C1| codons 1-440 PISPIETVPVQLKPGMDGPKVKQWPLTEEKIKALTEICLEMEKEGKISRIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPRVINETPGIRYQYNVLPQGWKGSPALFQASMTKILQPFRTKNPEMVI YQYVDDLLVGSDLEIGQHRAKIEELREHLLKWGFTTPDQKHQKEPPFLWMGYELHPDKWT VQQIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVTLTEEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQDQWTYQIYQEPFKILKTGKYAKRRSA HTNDVKQLTEVVQKVTMESIVIWGKAPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETF |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48W | M36I, R41K, I64M, H69K, L89M |
| >A2536_C1| codons 21-99 EALLDTGADDTVLEEINLPGKWKPKMIWGIGGFIKVRQYDQILMEICGKKAIGTVLVGPT PVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Sylla, M | Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. | Antivir Ther, 2008 |