<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
A013 A013_C2 Burkina Faso 2006 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V N348I K103N P225H V35T, E36D, S162A, K173T, Q174K, D177E, T200A, Q207E, V245K, E248D, D250E, S251H, A272P, K281R, T286A, V292I, I293V, P294T, R307K, S322T, I326V, G335D, R356K, M357Q, G359S, A371V, I375V, A376S, K390R, A400T, T403R, E432D, V435M I159L
>A013_C2| codons 1-440
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPALFQASMTKILEPFRTKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEHPFLWMGYELHPDKWT
VQPIKLPDKEHWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTEIVTLTEEAE
LELAENKEILKEPVHGVYYDPTKDLVAEIQKQGQDQWTYQIYQEPFKILKTGKYAKQRSA
HTNDVKQLTEVVQKVSTESIVIWGKTPKFRLPIQKETWETWWREYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIMGAETF

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13A, K14R, K20I, M36I, N37D, R41K, L63S, H69K, L89M  
>A013_C2| codons 1-99
PQITLWQRPLVTARIGGQLIEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD
QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Sylla, M Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. Antivir Ther, 2008