<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
D673 D673_C2 Burkina Faso 2006 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69D, M184V, T215Y   V106A, M230L V108I, F227L V35T, E44D, L109I, K122E, D123N, S162A, S163R, K173T, Q174K, D177E, T200A, I202V, Q207G, R211K, K223Q, L228R, P243S, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, T386I, K390R, E399D, A400T, E432D, V467I, T470P, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534S S105V, M164H, T165D
>D673_C2| codons 1-552
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKDGKISKIGPENPYNTPV
FAIKKKDSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKVATIIDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQARHDKILEPFRTKNPEIVI
YQYVDDLYVGSDLEIGQHRAKVEELRGHLLKWGFYTPDKKHQQEPPLRWLGYELHPDKWT
VQSIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA
HTNDVKQLTEVVQKVATESIVIWGKIPKFRLPIQKETWDTWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVISLPETTNQKTELH
AIYLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEKLIGKDKVYLSWVPAHK
GIGGNEQVDKLV

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, G16E, L19Q, K20I, M36I, R41K, H69K, K70R, L89M  
>D673_C2| codons 1-99
PQITLWQRPLVTVRIEGQQIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Sylla, M Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. Antivir Ther, 2008