<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
D607 D607_C2 Burkina Faso 2006 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, L210W, T215Y   K101E, G190A   I5V, E6K, K11T, V35T, E36A, T39K, K43E, E53D, K102Q, K122E, D123S, I135T, E138A, S162D, K173S, V179I, T200A, Q207A, R211K, V245Q, T286A, E291D, I293V, P294T, E312D, I326V, G335D, R356K, M357K, G359S, K366R, T369V, A371V, I375V, A376V, T386A, K390R, A400T, T403M, W410Y, E432D, V435A  
>D607_C2| codons 1-440
PISPVKTVPVTLKPGMDGPKVKQWPLTEEKIKALTAICKELEEEGKISKIGPDNPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEQKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRSQNPDIII
YQYVDDLYVASDLEIGQHRAKIEELRAHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVTLTEEAE
LELAENREILKDPVHGVYYDPSKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA
HTNDVRQLVEVVQKVVTESIVIWGKAPKFRLPIQKETWETWWMEYWQATYIPEWEFVNTP
PLVKLWYQLEKDPIAGAETF

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K14R, E35D, M36I, R41K, H69K, L89M  
>D607_C2| codons 1-99
PQITLWQRPIVTVRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Sylla, M Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. Antivir Ther, 2008