Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| C1078 | C10781_C1 | Mali | 2006 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, K14R, I15L, K20I, M36I, R41K, L63S, H69K, K70R, L89M |
| >C10781_C1| codons 1-99 PQITLWQRPIVTVRLGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QISIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | K103N | A98G, V179E | K20R, E28K, V35T, E36D, K122E, I135T, I142V, S162A, E169A, K173T, Q174S, D177E, T200A, Q207E, L228R, V245Q, D250E, T286A, I293V, P294T, E312D, I326V, M357K, R358T, G359S, K366R, T369V, A371V, I375V, A376V, T386A, A400T, T403M, E432D, V435A |
| >C10781_C1| codons 1-440 PISPIETVPVKLKPGMDGPRVKQWPLTKEKIKALTDICTELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQASMTKILAPFRTSNPEIEI YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFYTPDKKHQKEPPFRWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVTLTEEAE LELAENREILKDPVHGVYYDPSKDLVAEIQKQGQGQWTYQIYQEPFKNLKTGKYARKTSA HTNDVRQLVEVVQKVVTESIVIWGKAPKFKLPIQKETWETWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIAGAETF |
References
| Author | Title | Citation |
| Sylla, M | Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. | Antivir Ther, 2008 |