<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
B7166 B7166_C2 Mali 2006 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+EFV NA
2 3TC+AZT+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, T215Y N348I K103N V179E T27S, E28K, K32I, V35T, E36D, T39K, K49R, V60I, K102Q, D123S, I135T, S162A, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, V245E, E248D, S251R, T286A, E291D, V292I, I293V, P294T, K311R, S322T, I326V, G335D, R356K, M357R, G359S, A371V, I375A, T377L, K390R, T403M, E432D, V435M, A446S, V467F, S468P  
>B7166_C2| codons 1-469
PISPIETVPVKLKPGMDGPKVKQWPLSKEKIIALTDICKELEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQNKSVTVLDVGDAYFSVPL
DKSFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMEI
YQYVDDLYVGSDLEIGQHRAKIEELRDHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPDKDRWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILREPVHGVYYDPTKDLVAEIQKQGQDQWTYQIYQEPFKILKTGKYAKRRSA
HTNDVKQLTEVVQKAALESIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIMGAETFYVDGASNRETKLGKAGYVTDRGRQKVFPL

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13A, K14R, K20I, M36I, R41K, K43R, H69K, K70R, L89I  
>B7166_C2| codons 1-99
PQITLWQRPLVTARIGGQLIEALLDTGADDTVLEEINLPGKWRPKMIGGIGGFIKVRQYD
QILIEICGKRAIGTVLVGPTPVNIIGRNILTQIGCTLNF

References
Author Title Citation
Sylla, M Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. Antivir Ther, 2008