<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
B7166 B7166_C1 Mali 2006 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+EFV NA
2 3TC+AZT+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T215Y   K103N V179E T27S, E28K, K32I, V35T, E36D, T39K, K49R, V60I, K102Q, D123S, I135T, S162A, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, L228R, V245E, E248D, T286A, E291D, V292I, I293V, P294T, K311R, S322T, I326V, G335D, R356K, M357R, G359S, A371V, I375A, T377L, K390R, A400V, T403M, E432D, V435M  
>B7166_C1| codons 1-441
PISPIETVPVKLKPGMDGPKVKQWPLSKEKIIALTDICKEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQNKSVTVLDVGDAYFSVPL
DKSFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMEI
YQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGFYTPDKKHQKEPPFRWMGYELHPDKWT
VQPIELPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILREPVHGVYYDPTKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRSA
HTNDVKQLTEVVQKAALESIVIWGKTPKFRLPIQKETWEVWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIMGAETFY

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13A, K14R, K20I, M36I, R41K, K43R, H69K, K70R, L89I  
>B7166_C1| codons 1-99
PQITLWQRPLVTARIGGQLIEALLDTGADDTVLEEINLPGKWRPKMIGGIGGFIKVRQYD
QILIEICGKRAIGTVLVGPTPVNIIGRNILTQIGCTLNF

References
Author Title Citation
Sylla, M Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. Antivir Ther, 2008