Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| B7127 | B7127_C1 | Mali | 2006 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+EFV+IDV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, G17E, K20I, E35N, M36I, R41K, K45R, R57K, L63S, H69K, K70R, I72T, L89M |
| >B7127_C1| codons 1-99 PQITLWQRPLVTVKIGEQLIEALLDTGADDTVLENINLPGKWKPRMIGGIGGFIKVKQYD QISIEICGKRATGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M | V75I, F116Y, K219N | Y181C, G190S | K20R, A33V, V35T, V60I, K122E, D123N, S162A, K166R, K173T, Q174R, D177E, T200A, Q207E, R211K, V245M, E248D, S251C, A272P, K277R, T286A, E291D, V292I, I293V, P294T, S322A, G335D, M357Q, G359S, K366R, T369A, A371V, I375V, A376S, K388R, K390R, K395R, T403M, E432D, V435A |
| >B7127_C1| codons 1-441 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKVLTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYYSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQASMTRILEPFRTRNPEIVI CQYMDDLYVSSDLEIGQHRAKIEELREHLLKWGFTTPDNKHQKEPPFLWMGYELHPDKWT VQPIMLPDKDCWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPAKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARQRSA HTNDVRQLAEVVQKVSTESIVIWGKTPRFRLPIQRETWEAWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIAGAETFY |
References
| Author | Title | Citation |
| Sylla, M | Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. | Antivir Ther, 2008 |