<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
B7127 B7127_C1 Mali 2006 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+EFV+IDV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, G17E, K20I, E35N, M36I, R41K, K45R, R57K, L63S, H69K, K70R, I72T, L89M  
>B7127_C1| codons 1-99
PQITLWQRPLVTVKIGEQLIEALLDTGADDTVLENINLPGKWKPRMIGGIGGFIKVKQYD
QISIEICGKRATGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Q151M V75I, F116Y, K219N Y181C, G190S   K20R, A33V, V35T, V60I, K122E, D123N, S162A, K166R, K173T, Q174R, D177E, T200A, Q207E, R211K, V245M, E248D, S251C, A272P, K277R, T286A, E291D, V292I, I293V, P294T, S322A, G335D, M357Q, G359S, K366R, T369A, A371V, I375V, A376S, K388R, K390R, K395R, T403M, E432D, V435A  
>B7127_C1| codons 1-441
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKVLTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYYSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQASMTRILEPFRTRNPEIVI
CQYMDDLYVSSDLEIGQHRAKIEELREHLLKWGFTTPDNKHQKEPPFLWMGYELHPDKWT
VQPIMLPDKDCWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPAKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARQRSA
HTNDVRQLAEVVQKVSTESIVIWGKTPRFRLPIQRETWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIAGAETFY

References
Author Title Citation
Sylla, M Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. Antivir Ther, 2008