Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A4197 | A4197_C1 | Mali | 2006 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+IDV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, G16E, K20I, M36I, P39L, L63S, H69K, L89I |
| >A4197_C1| codons 1-99 PQITLWQRPLVTVKIEGQLIEALLDTGADDTVLEEINLLGRWKPKMIGGIGGFIKVRQYD QISIEICGKKAIGTVLVGPTPVNIIGRNILTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11N, V35T, K122E, D123N, S162A, K173T, Q174K, D177E, Q197K, T200A, I202V, Q207K, R211E, V245Q, E248D, T286A, I293V, P294T, S322T, G335D, R356K, M357K, G359S, T369A, A371V, I375A, K390R, A400T, E432D |
| >A4197_C1| codons 1-440 PISPIETVPVNLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI YQYMDDLYVGSDLEIGKHRAKVEELRKHLLEWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVTLTEEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVKQLAEVVQKAATESIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETF |
References
| Author | Title | Citation |
| Sylla, M | Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. | Antivir Ther, 2008 |