Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A2840 | A2840_C2 | Mali | 2006 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+IDV | NA |
| 2 | 3TC+AZT+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215F | K103N | P225H | V35T, E36D, K122E, D123N, I132V, I135T, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, T286A, V292I, I293V, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, A376S, K390R, A400T, E432D, A446S, R448K, D471E, Q480H, H483Y, L491S, E492T |
| >A2840_C2| codons 1-508 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DENFRKYTAFTVPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLFTPDKKHQKEHPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEIVPLTEEAE LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVKQLTEVVQKVSTESIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGASNKETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIYLALQDSGSTVNIVTDSQYALGIIQA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12A, I13V, K14R, K20I, M36I, R41K, L63P, H69K, L89M |
| >A2840_C2| codons 1-99 PQITLWQRPLVAVRIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Sylla, M | Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. | Antivir Ther, 2008 |