Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A2608 | A2608_C2 | Mali | 2006 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | NA |
| 2 | 3TC+AZT+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215Y | K103N, Y188L, M230L | V35T, K49R, V60I, S105T, I135V, S162A, K173A, Q174K, D177E, G196E, T200A, Q207E, V245Q, I257V, A272P, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, K366R, A371V, I375V, A376S, K390R, A400T, T403M, E432D, V435A, S468T, T470P, D471E, Q480H, L491S, K512R, S519N, Q524K |
| >A2608_C2| codons 1-525 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKTVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPEIVI YQYVDDLLVGSDLEIEQHRAKIEELREHLLRWGFYTPDKKHQKEPPFLWLGYELHPDKWT VQPIQLPEKDSWTVNDVQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVRQLTEVVQKVSTESIVIWGKTPKFRLPIQKETWETWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIAGAETFYVDGAANRETKLGKAGYVTDRGRQKVVTLPETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V11I | L10I, I13V, I15V, L19P, K20I, M36I, R41K, L63S, H69K, K70R, L89M |
| >A2608_C2| codons 1-99 PQITLWQRPIITVKVGGQPIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QISIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Sylla, M | Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. | Antivir Ther, 2008 |