Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A2546 | A2546_C1 | Mali | 2006 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | 13 |
| 2 | 3TC+AZT+NVP | 13 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215F | K103N, Y181C | P225H | V35T, S68G, K122E, I135V, S162T, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, H221Y, V241I, P243T, V245Q, K281R, L283I, T286A, E291D, V292I, I293V, P294T, L295M, S322A, G335D, R356K, M357K, G359S, A371V, I375V, K390R, A400T, T403R, E432D, V435M, V467I, T470S, D471E, Q480H, L491S |
| >A2546_C1| codons 1-499 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQTSMTKILEPFRTKNPEMVI CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFFTPDKKYQKEHPFLWMGYELHPDKWT IQTIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLIRGAKALTDIVTMTEEAE LELAENREILKEPVHGVYYDPAKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVKQLTEVVQKVATESIVIWGKTPKFRLPIQKETWETWWREYWQATWIPEWEFVNTP PLVKLWYQLEKDPIMGAETFYVDGAANRETKLGKAGYVTDRGRQKVISLSETTNQKTELH AIHLALQDSGSEVNIVTDS |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, L19P, K20I, M36I, N37D, R41K, I64L, H69K, K70R, L89M |
| >A2546_C1| codons 1-99 PQITLWQRPLVTVKIGGQPIEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD QILLEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Sylla, M | Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. | Antivir Ther, 2008 |