Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| a2521 | a2521_c1 | Mali | 2006 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+IDV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, G16E, K20I, M36I, R41K, L63H, H69K, L89M |
| >a2521_c1| codons 1-99 PQITLWQRPLVTVRIEGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIHIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36D, K43R, K49R, V60I, K66N, S68R, K122E, I135V, S162A, K173R, Q174K, D177E, T200A, Q207E, R211K, V245K, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, K366R, A371V, I375V, A376S, K390R, E399D, T403M, E432D, E438K |
| >a2521_c1| codons 1-440 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEREGKISRIGPENPYNTPI FAIKKNDRTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRRKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVRQLTEVVQKVSTESIVIWGKTPKFRLPIQKETWDAWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAKTF |
References
| Author | Title | Citation |
| Sylla, M | Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. | Antivir Ther, 2008 |