<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
4420 4420_2004 Romania 2004 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, T12N, K14R, I15V, K20R, E35D, M36I, N37D, R41K, K45KR, R57K, L63T, E65D, I72T  
>4420_2004| codons 1-99
PQITLWQRPVVNIRVGGQLREALLDTGADDTVLEDIDLPGKWKPRMIGGIGGFIKVKQYD
QITIDICGHKATGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35P, T39A, E40D, V60I, K101KR, D123E, I135L, E138A, K173A, Q174K, I195L, T200K, Q207A, R211K, V245Q, E248D, A272P, R284K, T286A, E291A, V292I, I293V, L295M, E297A, V317A  
>4420_2004| codons 1-326
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALPEICADMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLRKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSLNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDIVI
YQYMDDLYVGSDLELGQHRKKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLKGAKALTAIVPMTAEAE
LELAENREILKEPVHGAYYDPSKDLI

References
Author Title Citation
Paraschiv, S Polymorphisms and resistance mutations in the protease and reverse transcriptase genes of HIV-1 F subtype Romanian strains. Int J Infect Dis, 2007