<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
2165 2165_2004 Romania 2004 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12A, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, H69HY, I72T, L89M  
>2165_2004| codons 1-99
PQITLWQRPLVAIKVEGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QITIDICGYKATGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      V179D V35T, T39A, E40D, I135L, I142IV, S162H, K166E, E169EK, K173IT, Q174K, I195L, G196E, T200TA, Q207A, R211K, V245Q, E248N, A272P, V276VI, L283I, T286A, E291D, V292I, I293V, P294T, E297A, K331N  
>2165_2004| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICADMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSLNNETPGVRYQYNVLPQGWKGSPAIFQHSMTEILKPFRTKNPDIDI
YQYMDDLYVGSDLELEQHRAKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLIRGAKALTDIVTLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQNQGQG

References
Author Title Citation
Paraschiv, S Polymorphisms and resistance mutations in the protease and reverse transcriptase genes of HIV-1 F subtype Romanian strains. Int J Infect Dis, 2007