Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 1704 | PRRT_1704 | Canada | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, M36L, I62V, L63AS, I64IV, I72V, I93L |
| >PRRT_1704| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEELNLPGRWKPKMIGGIGGFIKVRQYD QVSVEICGHKAVGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K102R, K122P, Q174K, N175NH, V179I, T200TA, I202V, Q207E, R211RK, E248D, A272S, T286A, I293V, E297KR, L301I, E312K, G333E, Q334A, E344ED, R356K, G359S, K385R, K390R |
| >PRRT_1704| codons 1-400 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRKKSVTVLDVGDAYFSVPL DPDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKKHPDIII YQYMDDLYVGSDLEIGQHRAKVEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTEVVPLTREAE IELAENREILKKPVHGVYYDPSKDLIAEIQKQEAGQWTYQIYQDPFKNLKTGKYAKMRSA HTNDVKQLTEAVQKIATESIVIWGRTPKFRLPIQKETWEA |
References
| Author | Title | Citation |
| Brumme, ZL | Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1. | PLoS Pathog, 2007 |