Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 1365 | PRRT_1365 | Canada | 1998 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, M36I, R41K, H69K, V82I, L89M |
| >PRRT_1365| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36D, T39TK, K122E, D123DN, K173S, Q174K, I178M, T200A, Q207A, R211KN, V245Q, E248D, D250E, S251D, L283I, E291D, V292I, I293V, P294T, E312N, I326V, R356K, M357K, R358G, G359A, Q367E, E370A, A371V, I375V, A376S, T386I, K390R |
| >PRRT_1365| codons 1-400 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICKEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPDMVI YQYMDDLYVGSDLEIGQHRAKIEELRAHLLNWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKEDWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLIRGTKALTDIVTLTEEAE LELAENREILKNPVHGVYYDPSKDLVAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKKGAA HTNDVKELTAVVQKVSTESIVIWGKIPKFRLPIQKETWEA |
References
| Author | Title | Citation |
| Brumme, ZL | Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1. | PLoS Pathog, 2007 |