Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 1258 | PR_1258 | Canada | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L10R, N37S, L63P, I64V | A28AS |
| >PR_1258| codons 1-99 PQITLWQRPRVTIKIGGQLKEALLDTGSDDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD QIPVEICGHKAIGTVLVGPTPVNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, L210W | D121H, K122E, I178L, V179I, T200I, I202V, R211K | V118VD |
| >RT_1258| codons 24-236 WPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKR TQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSDPLHEDFRKYTAFTIPSINNETPGIR YQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDLIIYQYVDDLYVGSDLEIGQHRIKVE ELRQHLWKWGFTTPDKKHQKEPPFLWMGYELHP |
References
| Author | Title | Citation |
| Brumme, ZL | Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1. | PLoS Pathog, 2007 |