<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
1101 PR_1101 Canada 1998 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  D30DE I13IV, L33V, N37NH, P39PS, R41K, I62IV, L63P, H69Y, I72IV  
>PR_1101| codons 1-99
PQITLWQRPLVTVKIGGQLKEALLDTGADETVVEEMHLSGKWKPKMIGGIGGFIKVRQYD
QVPIEICGYKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K49R, V60I, V106I, K122E, D177E, I178M, T200A, Q207G, H208Y, R211K L149LF
>RT_1101| codons 24-236
WPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKR
TQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIR
YQYNVFPQGWKGSPAIFQSSMTKILEPFRKQNPEMVIYQYMDDLYVGSDLEIGQHRAKIE
ELRGYLLKWGFTTPDKKHQKEPPFLWMGYELHP

References
Author Title Citation
Brumme, ZL Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1. PLoS Pathog, 2007