<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
1075 PR_1075 Canada 1998 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L33V, N37T, P39S, R41K, L63P, I64V, H69Y Q61HY
>PR_1075| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVVEEMTLSGKWKPKMIGGIGGFIKVRQYD
YIPVEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E40D, K49R, V60I, D121DY, K122E, I159IV, D177E, T200I, Q207G, R211K  
>RT_1075| codons 24-236
WPLTEEKIKALTEICTDMEKEGKISRIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKR
TQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLYEDFRKYTAFTIPSINNETPGIR
YQYNVLPQGWKGSPAVFQSSMTKILEPFRKQNPEIVIYQYMDDLYVGSDLEIGQHRIKIE
ELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHP

References
Author Title Citation
Brumme, ZL Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1. PLoS Pathog, 2007