Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CTL 018 | CTL 018 | Denmark | 2007 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E10D, E13Q, K34R, M50I, I72V, L101I, K111T, T124N, I135V, I220L |
| >CTL 018| codons 1-288 FLDGIDKAQDEHQKYHSNWRAMASDFNLPPVVAREIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVTTIHTDNGSN FTSNTVKAACWWAGVKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKLQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12P, E35D, M36I, R57K, D60E, L63S, I64V, V77I, I93L |
| >CTL 018| codons 1-99 PQITLWQRPLVPIKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYE QISVEICGHKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| R83K, E169D, R211K, T286A, I293V, V317A, D324E, T386I, A400V, T403A, P421L, D460N, R461K, L469I, H483L, L491V, I495V |
| >CTL 018| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLTEEAE LELAENREILKEPVHGAYYDPSKELIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA HTNDVKQLTEAVQKIATESIVIWGKIPKFKLPIQKETWEVWWAEYWQATWIPEWEFVNTP LLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVSITDTTNQKTELQ AILLALQDSGVEVNVVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSAGIRKVL |
References
| Author | Title | Citation |
| Andresen, BS | Characterization of near full-length genomes of HIV type 1 strains in Denmark: basis for a universal therapeutic vaccine. | ARHR, 2007 |