Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PMVL 039 | PMVL 039 | Denmark | 2004 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S39C, L45V, L101I, M154I, V165I, R187K, K211R, K215N |
| >PMVL 039| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVACCDKCQVKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKTIHTDNGSN FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESINKELKKIIGQIRDQAEHLKTAVQMAV FIHNFKKKGGIGGYSAGERIVDIIATDIQTRELQNQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12M, K14R, N37D, L63P, I64V, H69N, V77I |
| >PMVL 039| codons 1-99 PQITLWQRPLVMIRIGGQLKEALLDTGADDTVLEEMDLPGRWKPKMIGGIGGFIKVRQYD QIPVEICGNKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V118I, D123E, I135T, V179VI, G196E, F214L, A272P, K277R, E297K, A360T, A376V, V381VI, A400T, V435I, D460N, R461K, H483Y, S519N, A554N |
| >PMVL 039| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYMDDLYVGSDLEIEQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGT HTNDVKQLTEAVQKIVTESIIIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTNKGRQKVVSLTDTTNQKTELQ AIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSNGIRKVL |
References
| Author | Title | Citation |
| Andresen, BS | Characterization of near full-length genomes of HIV type 1 strains in Denmark: basis for a universal therapeutic vaccine. | ARHR, 2007 |