Surveillance Drug Resistance Mutation (SDRM) Worksheet
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RT Table Excel spreadsheet Table in tab-delimited format
| | Prevelance in naive patients (%) by subtype | Max % | Max % | Overall |
| | A | AE | AG | B | C | D | F | G | Other | Naive | w/ Rx | % w/ Rx |
Pos | AA | HIVDB | ANRS | Rega | IAS | LA | Total | (1448) | (580) | (866) | (5420) | (1914) | (307) | (253) | (382) | (1043) | (12213) | (15084) | (15084) |
| 67 | N | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 44.0 | 30.0 |
| 210 | W | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 25.0 | 20.0 |
| 106 | M | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 14.0 | 1.3 |
| 219 | E | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 9.4 | 4.9 |
| 225 | H | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 8.7 | 2.1 |
| 151 | M | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 6.0 | 2.6 |
| 100 | I | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 5.4 | 2.6 |
| 190 | S | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 5.2 | 1.5 |
| 115 | F | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 2.0 | 1.3 |
| 70 | E | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.6 | 0.3 |
| 101 | P | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.4 | 0.5 |
| 69 | ins | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.3 | 1.0 |
| 181 | V | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.2 | 0.2 |
| 179 | F | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.7 | 0.2 |
| 215 | Y | 1 | 1 | 1 | 1 | 1 | 5 | 0.1 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 38.0 | 33.0 |
| 215 | F | 1 | 1 | 1 | 1 | 1 | 5 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 21.0 | 10.0 |
| 106 | A | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 1.9 | 1.2 |
| 188 | C | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.1 | 1.3 | 0.3 |
| 181 | I | 1 | 1 | 1 | 1 | 1 | 5 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 1.0 | 0.4 |
| 181 | C | 1 | 1 | 1 | 1 | 1 | 5 | 0.1 | 0.2 | 0.1 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 16.0 | 11.0 |
| 65 | R | 1 | 1 | 1 | 1 | 1 | 5 | 0.1 | 0.0 | 0.0 | 0.0 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 6.5 | 3.1 |
| 103 | N | 1 | 1 | 1 | 1 | 1 | 5 | 0.1 | 0.0 | 0.2 | 0.3 | 0.3 | 0.0 | 0.0 | 0.0 | 0.3 | 0.3 | 40.0 | 22.0 |
| 70 | R | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.3 | 0.0 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.3 | 29.0 | 24.0 |
| 190 | A | 1 | 1 | 1 | 1 | 1 | 5 | 0.1 | 0.0 | 0.0 | 0.0 | 0.1 | 0.3 | 0.0 | 0.0 | 0.1 | 0.3 | 15.0 | 7.5 |
| 74 | V | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.3 | 0.0 | 0.3 | 11.0 | 7.4 |
| 101 | E | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.3 | 0.1 | 0.0 | 0.0 | 0.0 | 0.1 | 0.3 | 7.1 | 3.6 |
| 188 | L | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.3 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.3 | 5.6 | 2.3 |
| 184 | I | 1 | 1 | 1 | 1 | 1 | 5 | 0.1 | 0.2 | 0.1 | 0.0 | 0.0 | 0.3 | 0.0 | 0.0 | 0.0 | 0.3 | 2.0 | 1.4 |
| 188 | H | 1 | 1 | 1 | 1 | 1 | 5 | 0.0 | 0.0 | 0.0 | 0.1 | 0.1 | 0.3 | 0.0 | 0.0 | 0.1 | 0.3 | 1.3 | 0.5 |
| 219 | Q | 1 | 1 | 1 | 1 | 1 | 5 | 0.1 | 0.5 | 0.5 | 0.0 | 0.0 | 0.3 | 0.0 | 0.0 | 0.1 | 0.5 | 25.0 | 14.0 |
| 98 | G | 1 | 1 | 1 | 1 | 1 | 5 | 0.1 | 0.0 | 0.2 | 0.2 | 0.5 | 0.0 | 0.0 | 0.3 | 0.0 | 0.5 | 8.4 | 3.7 |
| 184 | V | 1 | 1 | 1 | 1 | 1 | 5 | 0.2 | 0.2 | 0.2 | 0.2 | 0.1 | 0.7 | 0.0 | 0.0 | 0.1 | 0.7 | 61.0 | 49.0 |
| 41 | L | 1 | 1 | 1 | 1 | 1 | 5 | 0.1 | 0.2 | 0.1 | 0.3 | 0.1 | 1.3 | 0.0 | 0.0 | 0.6 | 1.3 | 39.0 | 34.0 |
| 179 | D | 1 | 1 | 1 | 1 | 1 | 5 | 0.3 | 1.7 | 0.0 | 2.0 | 0.5 | 0.0 | 4.1 | 0.0 | 1.0 | 4.1 | 4.5 | 1.7 |
| 106 | I | 1 | 1 | 1 | 1 | 1 | 5 | 1.3 | 4.7 | 0.5 | 2.1 | 0.0 | 2.6 | 4.7 | 1.6 | 2.2 | 4.7 | 7.3 | 2.2 |
| 44 | A | 1 | 1 | 1 | | 1 | 4 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 2.8 | 1.3 |
| 75 | T | 1 | 1 | 1 | | 1 | 4 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 2.7 | 1.1 |
| 190 | Q | 1 | 1 | 1 | | 1 | 4 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.1 |
| 190 | C | 1 | 1 | 1 | | 1 | 4 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.1 |
| 190 | T | 1 | 1 | 1 | | 1 | 4 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 69 | D | 1 | 1 | 1 | | 1 | 4 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 7.2 | 6.0 |
| 74 | I | 1 | 1 | 1 | | 1 | 4 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 3.0 | 2.5 |
| 219 | R | 1 | 1 | 1 | | 1 | 4 | 0.1 | 0.0 | 0.1 | 0.1 | 0.1 | 0.0 | 0.0 | 0.0 | 0.1 | 0.1 | 2.3 | 1.9 |
| 190 | E | 1 | 1 | 1 | | 1 | 4 | 0.0 | 0.0 | 0.1 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 1.4 | 0.4 |
| 103 | T | 1 | 1 | 1 | | 1 | 4 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.9 | 0.2 |
| 103 | S | 1 | 1 | 1 | | 1 | 4 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.6 | 0.5 |
| 67 | G | 1 | 1 | 1 | | 1 | 4 | 0.0 | 0.0 | 0.1 | 0.2 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 2.5 | 1.8 |
| 190 | V | 1 | 1 | 1 | | 1 | 4 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.3 | 0.0 | 0.0 | 0.0 | 0.3 | 0.0 | 0.0 |
| 69 | N | 1 | 1 | 1 | | 1 | 4 | 0.1 | 0.5 | 0.0 | 0.4 | 0.1 | 0.0 | 0.4 | 0.0 | 0.3 | 0.5 | 6.4 | 5.8 |
| 75 | M | 1 | 1 | 1 | | 1 | 4 | 0.1 | 0.5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.5 | 3.6 | 2.0 |
| 219 | N | 1 | 1 | 1 | | 1 | 4 | 0.1 | 0.5 | 0.2 | 0.1 | 0.1 | 0.0 | 0.0 | 0.0 | 0.1 | 0.5 | 2.5 | 2.0 |
| 69 | A | 1 | 1 | 1 | | 1 | 4 | 0.1 | 0.0 | 0.1 | 0.3 | 0.1 | 0.7 | 0.8 | 0.0 | 0.2 | 0.8 | 1.8 | 0.9 |
| 44 | D | 1 | 1 | 1 | | 1 | 4 | 0.3 | 0.0 | 0.2 | 0.2 | 0.3 | 1.3 | 0.8 | 0.3 | 0.1 | 1.3 | 8.9 | 7.5 |
| 108 | I | 1 | | 1 | 1 | 1 | 4 | 0.3 | 0.4 | 1.3 | 0.6 | 0.3 | 0.0 | 0.0 | 0.0 | 0.7 | 1.3 | 4.9 | 3.6 |
| 230 | L | 1 | 1 | 1 | | | 3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 3.4 | 1.0 |
| 75 | S | 1 | 1 | 1 | | | 3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.4 | 0.2 |
| 215 | V | 1 | 1 | 1 | | | 3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.9 | 0.7 |
| 67 | del | 1 | | 1 | | 1 | 3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.1 |
| 103 | H | | 1 | 1 | | 1 | 3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 227 | C | 1 | | 1 | | 1 | 3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 238 | T | 1 | | 1 | | 1 | 3 | 0.0 | 0.0 | 0.0 | 0.1 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 4.2 | 1.7 |
| 215 | I | 1 | 1 | 1 | | | 3 | 0.1 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 4.2 | 1.3 |
| 67 | E | 1 | 1 | | | 1 | 3 | 0.0 | 0.0 | 0.1 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 1.3 | 0.7 |
| 215 | E | 1 | 1 | 1 | | | 3 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.1 | 1.1 | 0.1 |
| 69 | G | 1 | | 1 | | 1 | 3 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.4 | 0.2 |
| 116 | Y | 1 | | | 1 | 1 | 3 | 0.0 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 3.7 | 2.1 |
| 215 | C | 1 | 1 | 1 | | | 3 | 0.0 | 0.0 | 0.0 | 0.2 | 0.1 | 0.0 | 0.0 | 0.0 | 0.1 | 0.2 | 3.3 | 1.0 |
| 75 | A | 1 | 1 | 1 | | | 3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 1.0 | 0.6 |
| 77 | L | 1 | | | 1 | 1 | 3 | 0.0 | 0.3 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.3 | 2.3 | 1.8 |
| 138 | K | 1 | | 1 | | 1 | 3 | 0.1 | 0.0 | 0.0 | 0.2 | 0.2 | 0.0 | 0.0 | 0.0 | 0.3 | 0.3 | 1.3 | 0.3 |
| 215 | S | 1 | 1 | 1 | | | 3 | 0.0 | 0.2 | 0.1 | 0.4 | 0.1 | 0.0 | 0.4 | 0.0 | 0.4 | 0.4 | 1.5 | 1.2 |
| 215 | D | 1 | 1 | 1 | | | 3 | 0.0 | 0.0 | 0.0 | 0.4 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.4 | 1.0 | 0.8 |
| 236 | L | 1 | | 1 | | 1 | 3 | 0.0 | 0.0 | 0.4 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.4 | 0.4 | 0.2 |
| 318 | F | 1 | | 1 | | 1 | 3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.5 | 0.0 | 0.0 | 0.0 | 0.2 | 0.5 | 1.3 | 1.1 |
| 101 | Q | 1 | | 1 | | 1 | 3 | 0.4 | 0.2 | 0.9 | 0.6 | 0.5 | 0.0 | 0.0 | 0.5 | 0.3 | 0.9 | 3.8 | 3.1 |
| 227 | L | 1 | | 1 | | 1 | 3 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.9 | 0.0 | 0.1 | 0.9 | 2.1 | 1.1 |
| 69 | S | 1 | 1 | | | 1 | 3 | 0.3 | 0.2 | 0.3 | 0.7 | 0.3 | 0.0 | 0.0 | 0.0 | 1.2 | 1.2 | 2.7 | 1.6 |
| 75 | I | 1 | | | 1 | 1 | 3 | 0.1 | 0.0 | 0.0 | 0.0 | 0.1 | 1.3 | 0.0 | 0.0 | 0.0 | 1.3 | 2.8 | 2.0 |
| 103 | R | 1 | | 1 | | 1 | 3 | 0.3 | 0.5 | 0.2 | 3.0 | 0.7 | 0.3 | 0.8 | 0.0 | 1.3 | 3.0 | 2.7 | 2.3 |
| 118 | I | 1 | | 1 | | 1 | 3 | 1.0 | 0.6 | 0.4 | 2.6 | 2.1 | 7.1 | 2.1 | 1.1 | 2.2 | 7.1 | 17.0 | 15.0 |
| 179 | E | 1 | | 1 | | 1 | 3 | 0.0 | 0.0 | 0.6 | 0.5 | 0.1 | 0.4 | 0.0 | 7.2 | 0.6 | 7.2 | 9.8 | 0.9 |
| 62 | V | 1 | | | 1 | 1 | 3 | 16.0 | 0.2 | 0.0 | 0.1 | 0.1 | 0.0 | 0.0 | 0.3 | 1.5 | 16.0 | 3.8 | 3.2 |
| 70 | S | 1 | | | | 1 | 2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.4 | 0.1 |
| 67 | S | 1 | | | | 1 | 2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.2 | 0.3 |
| 219 | W | 1 | | | | 1 | 2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.1 | 0.3 |
| 70 | G | 1 | | 1 | | | 2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.9 | 0.4 |
| 215 | H | | 1 | 1 | | | 2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.1 |
| 215 | G | | 1 | 1 | | | 2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 101 | N | 1 | | 1 | | | 2 | 0.0 | 0.0 | 0.1 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.9 | 0.2 |
| 215 | N | | 1 | 1 | | | 2 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.9 | 0.2 |
| 234 | I | | | 1 | | 1 | 2 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.7 | 0.1 |
| 215 | L | | 1 | 1 | | | 2 | 0.1 | 0.0 | 0.0 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 1.1 | 0.1 |
| 65 | N | 1 | | 1 | | | 2 | 0.0 | 0.0 | 0.0 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.4 | 0.1 |
| 103 | Q | 1 | | | | 1 | 2 | 0.1 | 0.3 | 0.1 | 0.1 | 0.1 | 0.0 | 0.0 | 0.0 | 0.2 | 0.3 | 0.8 | 0.1 |
| 103 | E | 1 | | | | 1 | 2 | 0.0 | 0.0 | 0.0 | 0.1 | 0.3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.3 | 0.7 | 0.1 |
| 215 | A | | 1 | 1 | | | 2 | 0.1 | 0.0 | 0.0 | 0.1 | 0.1 | 0.0 | 0.0 | 0.3 | 0.0 | 0.3 | 0.3 | 0.2 |
| 333 | D | 1 | | | | 1 | 2 | 0.0 | 0.0 | 0.0 | 0.4 | 0.1 | 0.0 | 0.0 | 0.0 | 0.8 | 0.8 | 1.8 | 1.3 |
| 75 | L | 1 | | | | 1 | 2 | 0.2 | 1.6 | 0.2 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.6 | 1.7 | 0.4 |
| 101 | R | 1 | | 1 | | | 2 | 0.3 | 1.0 | 0.5 | 0.9 | 0.9 | 0.7 | 1.6 | 0.3 | 0.8 | 1.6 | 1.1 | 0.9 |
| 90 | I | | 1 | | 1 | | 2 | 0.3 | 0.7 | 6.9 | 1.8 | 1.0 | 1.8 | 0.0 | 0.8 | 1.5 | 6.9 | 7.4 | 4.6 |
| 333 | E | 1 | | | | 1 | 2 | 0.3 | 0.0 | 0.0 | 7.5 | 1.0 | 4.2 | 1.8 | 1.6 | 3.5 | 7.5 | 11.0 | 8.6 |
| 179 | I | 1 | | 1 | | | 2 | 42.0 | 14.0 | 1.7 | 4.0 | 1.9 | 4.6 | 5.8 | 0.3 | 6.2 | 42.0 | 55.0 | 7.8 |
| 98 | S | 1 | 1 | | | | 2 | 0.8 | 0.7 | 1.4 | 5.8 | 3.5 | 0.0 | 0.0 | 72.0 | 2.8 | 72.0 | 88.0 | 9.9 |
| 101 | H | 1 | | | | | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.4 | 0.4 |
| 318 | T | | | 1 | | | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.1 | 0.0 |
| 69 | E | 1 | | | | | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.7 | 0.1 |
| 238 | S | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.7 | 0.1 |
| 67 | T | 1 | | | | | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.6 | 0.3 |
| 67 | H | 1 | | | | | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.4 | 0.1 |
| 119 | S | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.4 | 0.0 |
| 219 | H | | | 1 | | | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.3 | 0.2 |
| 69 | del | 1 | | | | | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.1 |
| 181 | S | 1 | | | | | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.1 |
| 151 | L | 1 | | | | | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.1 |
| 227 | Y | 1 | | | | | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.1 |
| 68 | Y | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.1 |
| 52 | R | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 161 | L | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 214 | F | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 112 | S | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 68 | ins | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 215 | Z | 1 | | | | | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 145 | M | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 156 | A | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 233 | E | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 179 | M | 1 | | | | | 1 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 1.9 | 0.1 |
| 70 | N | 1 | | | | | 1 | 0.0 | 0.0 | 0.0 | 0.1 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 1.2 | 0.2 |
| 219 | T | 1 | | | | | 1 | 0.0 | 0.0 | 0.0 | 0.1 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 1.1 | 0.1 |
| 188 | F | | | 1 | | | 1 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 1.0 | 0.2 |
| 89 | G | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.9 | 0.1 |
| 100 | V | 1 | | | | | 1 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.6 | 0.1 |
| 54 | D | | | | | 1 | 1 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.4 | 0.0 |
| 92 | I | | | | | 1 | 1 | 0.1 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.3 | 0.0 |
| 101 | I | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.3 | 0.0 |
| 88 | G | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 |
| 184 | T | | | | | 1 | 1 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 |
| 106 | L | 1 | | | | | 1 | 0.1 | 0.2 | 0.1 | 0.1 | 0.1 | 0.0 | 0.0 | 0.0 | 0.2 | 0.2 | 1.0 | 0.1 |
| 157 | S | | | | | 1 | 1 | 0.0 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.6 | 0.1 |
| 70 | T | 1 | | | | | 1 | 0.1 | 0.2 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.6 | 0.2 |
| 89 | K | | | | | 1 | 1 | 0.1 | 0.2 | 0.0 | 0.1 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.6 | 0.1 |
| 190 | R | | | | | 1 | 1 | 0.0 | 0.2 | 0.2 | 0.1 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.2 | 0.1 |
| 62 | T | | | | | 1 | 1 | 0.0 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.1 | 0.1 |
| 208 | Y | | | | | 1 | 1 | 0.0 | 0.0 | 0.1 | 0.3 | 0.1 | 0.0 | 0.0 | 0.0 | 0.2 | 0.3 | 11.0 | 6.5 |
| 139 | I | | | | | 1 | 1 | 0.3 | 0.0 | 0.1 | 0.2 | 0.1 | 0.0 | 0.0 | 0.3 | 0.3 | 0.3 | 1.8 | 0.3 |
| 67 | A | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.3 | 0.2 | 0.0 | 0.0 | 0.0 | 0.2 | 0.3 | 0.6 | 0.2 |
| 227 | S | 1 | | | | | 1 | 0.0 | 0.0 | 0.0 | 0.1 | 0.1 | 0.3 | 0.0 | 0.0 | 0.1 | 0.3 | 0.3 | 0.1 |
| 143 | S | | | | | 1 | 1 | 0.1 | 0.0 | 0.0 | 0.3 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.3 | 0.1 | 0.1 |
| 221 | Y | | | 1 | | | 1 | 0.0 | 0.2 | 0.3 | 0.1 | 0.1 | 0.4 | 0.4 | 0.0 | 0.2 | 0.4 | 8.1 | 4.2 |
| 218 | E | | | | | 1 | 1 | 0.1 | 0.0 | 0.1 | 0.0 | 0.1 | 0.0 | 0.4 | 0.3 | 0.1 | 0.4 | 7.3 | 5.5 |
| 165 | A | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.3 | 0.4 | 0.0 | 0.0 | 0.0 | 0.4 | 0.9 | 0.1 |
| 88 | S | | | | | 1 | 1 | 0.1 | 0.2 | 0.0 | 0.1 | 0.4 | 0.0 | 0.4 | 0.0 | 0.1 | 0.4 | 0.6 | 0.2 |
| 179 | A | 1 | | | | | 1 | 0.0 | 0.4 | 0.0 | 0.3 | 0.2 | 0.0 | 0.0 | 0.0 | 0.4 | 0.4 | 0.4 | 0.2 |
| 179 | G | 1 | | | | | 1 | 0.0 | 0.2 | 0.1 | 0.1 | 0.1 | 0.4 | 0.4 | 0.0 | 0.1 | 0.4 | 0.4 | 0.2 |
| 145 | L | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.4 | 0.0 | 0.0 | 0.0 | 0.4 | 0.0 | 0.0 |
| 141 | E | | | | | 1 | 1 | 0.2 | 0.0 | 0.1 | 0.0 | 0.0 | 0.4 | 0.0 | 0.0 | 0.1 | 0.4 | 0.0 | 0.0 |
| 238 | N | 1 | | | | | 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.5 | 0.0 | 0.0 | 0.5 | 1.8 | 0.4 |
| 210 | S | 1 | | | | | 1 | 0.1 | 0.5 | 0.0 | 0.2 | 0.2 | 0.0 | 0.0 | 0.3 | 0.1 | 0.5 | 1.0 | 0.3 |
| 203 | K | | | | | 1 | 1 | 0.2 | 0.0 | 0.6 | 0.1 | 0.3 | 0.0 | 0.8 | 0.3 | 0.4 | 0.8 | 10.0 | 4.5 |
| 335 | C | | | | | 1 | 1 | 0.6 | 0.0 | 0.0 | 0.8 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.8 | 0.4 | 0.3 |
| 43 | Q | | | | | 1 | 1 | 0.5 | 0.4 | 1.0 | 0.1 | 0.3 | 0.4 | 0.4 | 0.0 | 0.2 | 1.0 | 4.0 | 3.2 |
| 179 | T | 1 | | | | | 1 | 1.1 | 0.4 | 0.0 | 0.1 | 0.1 | 1.1 | 0.0 | 0.0 | 0.1 | 1.1 | 1.3 | 0.2 |
| 210 | M | 1 | | | | | 1 | 0.3 | 1.1 | 0.0 | 0.3 | 0.0 | 0.0 | 0.4 | 0.0 | 0.2 | 1.1 | 1.0 | 0.2 |
| 68 | N | | | | | 1 | 1 | 0.3 | 0.0 | 0.1 | 0.2 | 0.2 | 1.1 | 0.4 | 0.0 | 0.0 | 1.1 | 0.9 | 0.3 |
| 236 | S | 1 | | | | | 1 | 1.1 | 0.0 | 0.0 | 0.0 | 0.1 | 0.3 | 0.0 | 0.0 | 0.0 | 1.1 | 0.5 | 0.0 |
| 69 | I | 1 | | | | | 1 | 0.0 | 0.2 | 0.0 | 0.1 | 0.5 | 0.0 | 1.2 | 0.0 | 0.0 | 1.2 | 1.8 | 0.5 |
| 210 | F | 1 | | | | | 1 | 0.2 | 1.2 | 0.1 | 0.9 | 0.2 | 0.0 | 0.0 | 0.3 | 0.5 | 1.2 | 1.7 | 0.8 |
| 348 | I | | | | | 1 | 1 | 0.0 | 0.0 | 0.0 | 0.2 | 0.0 | 1.3 | 0.0 | 0.0 | 0.0 | 1.3 | 19.0 | 7.2 |
| 135 | M | | | | | 1 | 1 | 0.5 | 1.5 | 0.2 | 0.8 | 0.8 | 0.4 | 0.0 | 0.3 | 1.1 | 1.5 | 2.8 | 1.8 |
| 312 | Q | | | | | 1 | 1 | 0.0 | 0.0 | 1.3 | 1.6 | 0.9 | 1.0 | 0.0 | 0.0 | 0.2 | 1.6 | 1.7 | 0.9 |
| 50 | V | | | | | 1 | 1 | 2.3 | 0.0 | 1.1 | 1.8 | 0.7 | 2.5 | 0.8 | 1.3 | 0.8 | 2.5 | 2.7 | 1.6 |
| 189 | I | | | | | 1 | 1 | 0.3 | 0.2 | 2.5 | 1.1 | 0.4 | 1.8 | 0.8 | 2.9 | 0.9 | 2.9 | 2.0 | 1.5 |
| 138 | A | | | | | 1 | 1 | 2.4 | 0.0 | 2.3 | 2.1 | 4.0 | 1.8 | 2.1 | 1.6 | 2.5 | 4.0 | 7.0 | 2.3 |
| 68 | G | | | | | 1 | 1 | 2.4 | 6.5 | 3.5 | 3.9 | 0.5 | 0.7 | 1.6 | 0.3 | 1.8 | 6.5 | 12.0 | 5.8 |
| 196 | E | | | | | 1 | 1 | 5.1 | 4.1 | 4.4 | 15.0 | 3.5 | 3.9 | 5.8 | 4.8 | 8.8 | 15.0 | 19.0 | 15.0 |
| 83 | K | | | | | 1 | 1 | 0.2 | 0.6 | 0.5 | 17.0 | 0.2 | 1.1 | 0.8 | 0.0 | 3.7 | 17.0 | 19.0 | 15.0 |
| 35 | I | | | | | 1 | 1 | 5.0 | 1.9 | 2.1 | 17.0 | 1.6 | 6.8 | 4.1 | 2.6 | 10.0 | 17.0 | 13.0 | 10.0 |
| 123 | G | | | | | 1 | 1 | 7.1 | 0.4 | 4.1 | 0.5 | 26.0 | 6.1 | 0.8 | 3.5 | 4.7 | 26.0 | 22.0 | 2.2 |
| 283 | I | | | | | 1 | 1 | 4.3 | 0.0 | 2.5 | 6.3 | 1.6 | 30.0 | 5.0 | 1.3 | 4.6 | 30.0 | 35.0 | 5.9 |
| 39 | A | | | | | 1 | 1 | 3.0 | 0.2 | 11.0 | 3.0 | 0.9 | 7.5 | 37.0 | 4.9 | 8.5 | 37.0 | 34.0 | 11.0 |
| 135 | L | | | | | 1 | 1 | 0.3 | 2.2 | 3.6 | 3.0 | 0.2 | 1.4 | 46.0 | 4.0 | 2.1 | 46.0 | 37.0 | 4.2 |
| 135 | T | | | | | 1 | 1 | 38.0 | 14.0 | 5.8 | 29.0 | 16.0 | 26.0 | 7.0 | 53.0 | 21.0 | 53.0 | 59.0 | 27.0 |
| 43 | E | | | | | 1 | 1 | 8.4 | 69.0 | 1.4 | 0.1 | 1.1 | 1.8 | 0.0 | 1.6 | 1.6 | 69.0 | 86.0 | 9.3 |
| 211 | K | | | | | 1 | 1 | 9.7 | 2.0 | 49.0 | 44.0 | 65.0 | 79.0 | 78.0 | 15.0 | 48.0 | 79.0 | 85.0 | 48.0 |
| 238 | R | 1 | | | | | 1 | 8.2 | 83.0 | 0.3 | 0.6 | 0.8 | 1.8 | 0.0 | 0.3 | 1.0 | 83.0 | 66.0 | 3.5 |
| 122 | E | | | | | 1 | 1 | 91.0 | 94.0 | 34.0 | 29.0 | 91.0 | 82.0 | 14.0 | 85.0 | 46.0 | 94.0 | 97.0 | 48.0 |
| 335 | D | | | | | 1 | 1 | 91.0 | 95.0 | 91.0 | 1.4 | 86.0 | 51.0 | 14.0 | 35.0 | 31.0 | 95.0 | 100.0 | 17.0 |