Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

HIV Home HBVseq HBV RT Mutations Blast Hits DB Release Notes

Query by HBV gp1 RT Mutation

Mutation A21S
Treatment NumN(t)RTIs = 0
Genotype D
IncludeMixtures No
References 27
Patients 110

AuthorRefIDPtIsolateAccessionCountryGenotypeRxReceivedNumMutsMutList
Osiowy (1985)73111GQ922000CanadaDNone421S, 122L, 130P, 332Y
  121GQ922001CanadaDNone721S, 122L, 130P, 248N, 263E, 266V, 278I
  131GQ922002CanadaDNone821S, 122L, 130P, 201L, 248N, 263E, 266V, 278I
Petzold (1986)25211AJ131956GermanyDNone1016T, 21S, 112I, 122L, 130P, 135Y, 248N, 256S, 263E, 278I
Chaudhuri (1992)12141AY373431IndiaDNone521S, 36K, 91I, 124Y, 213T
Rao (1997)17911U95551USADNone521S, 122L, 130P, 135Y, 278I
Garfein (1998)6311AY902768USADNone821S, 54H, 122L, 130P, 135Y, 164M, 215H, 271D
  21AY902769USADNone1121S, 54H, 122L, 130P, 135Y, 164M, 215H, 248N, 256S, 263E, 271D
  31AY902770USADNone1121S, 54H, 122L, 130P, 135Y, 164M, 215H, 248N, 256S, 263E, 271D
  41AY902771USADNone1121S, 54H, 122L, 130P, 135Y, 164M, 215H, 248N, 256S, 263E, 271D
  51AY902772USADNone1121S, 54H, 122L, 130P, 135Y, 164M, 215H, 248N, 256S, 263E, 271D
  61AY902773USADNone1121S, 54H, 122L, 130P, 135Y, 164M, 215H, 248N, 256S, 263E, 271D
  71AY902774USADNone1121S, 54H, 122L, 130P, 135Y, 164M, 215H, 248N, 256S, 263E, 271D
  81AY902776USADNone1121S, 54H, 122L, 130P, 135Y, 164M, 215H, 248N, 256S, 263E, 271D
  91AY902777USADNone1221S, 54H, 122L, 130P, 135Y, 164M, 212N, 215H, 248N, 256S, 263E, 271D
Tallo (1998)1111EU594382RussiaDNone721S, 122L, 248N, 263E, 271D, 329T, 342V
  331EU594434EstoniaDNone821S, 91I, 122L, 130P, 139T, 248N, 256S, 263E
  341EU594435EstoniaDNone621S, 122L, 248N, 263E, 271D, 332Y
  351EU594436RussiaDNone521S, 122L, 164M, 263E, 271D
Weinberger (1998)631AF065112GermanyDNone816T, 21S, 115V, 122L, 130P, 135Y, 148S, 193G
  91AF065118GermanyDNone621S, 122V, 130P, 135Y, 151Y, 222S
Jeantet (2001)20221AJ344117FranceDNone821S, 122L, 130P, 135Y, 248N, 256S, 263E, 278I
Kimbi (2003)58181AY233292AfricaDNone1021S, 112I, 115V, 122L, 130P, 248N, 263E, 278I, 326I, 336M
  191AY233293AfricaDNone1221S, 115V, 122L, 130P, 213P, 248N, 263E, 271Q, 278I, 319P, 326I, 336M
  201AY233294AfricaDNone1321S, 112I, 115V, 122L, 129L, 130P, 186T, 193K, 221Y, 248N, 263E, 326I, 336M
  211AY233295AfricaDNone821S, 115V, 122L, 130P, 248N, 263E, 266V, 278I
  221AY233296AfricaDNone1021S, 122L, 124N, 130P, 131D, 248N, 259P, 260W, 263E, 278I
Banerjee (2005)311DQ315776IndiaDNone621S, 122L, 124N, 130P, 135Y, 278I
  21DQ315777IndiaDNone87T, 21S, 122L, 128N, 181T, 248N, 263E, 266K
Elkady (2005)11141AB270537MongoliaDNone821S, 53D, 122L, 130P, 157M, 263E, 267R, 271D
Michitaka (2005)8211AB210819JapanDNone421S, 122L, 135Y, 278I
Odgerel (2005)10621DQ111987MongoliaDNone721S, 31N, 122L, 248N, 263E, 271D, 332Y
Olinger (2005)1531EU414105BelarusDNone416IT, 21S, 122L, 215*PQS
  41EU414106BelarusDNone521S, 122L, 248N, 256S, 257W
  51EU414107BelarusDNone521S, 122L, 248N, 256S, 257W
  61EU414108BelarusDNone821S, 97T, 122L, 130P, 131H, 248N, 256S, 257W
  341EU414141BelarusDNone721S, 122L, 248N, 256CS, 257*CWY, 263E, 271D
  351EU414142BelarusDNone916IT, 21S, 122L, 215PS, 248N, 256CS, 257*CWY, 263E, 271D
  361EU414143BelarusDNone821S, 97T, 122L, 130P, 131H, 248N, 263E, 309K
Andernach (2006)2111FJ692502HaitiDNone321S, 29F, 130P
  21FJ692503HaitiDNone421S, 122L, 130P, 248N
  31FJ692504HaitiDNone521S, 38S, 122L, 130P, 248N
  41FJ692505HaitiDNone621S, 122L, 130P, 135Y, 154Q, 248N
  51FJ692506HaitiDNone521S, 122L, 130P, 135Y, 248N
  61FJ692507HaitiDNone521S, 122L, 130P, 135Y, 248N
Chauhan (2006)8911EF103275IndiaDNone521S, 115V, 223S, 271D, 278I
  31EF103277IndiaDNone421S, 85C, 89N, 122L
  111EF103285IndiaDNone621S, 58C, 114C, 122L, 248N, 263E
Mrani (2007)17411AM422939FranceDNone88Q, 21S, 122L, 130P, 131D, 135Y, 263E, 278I
Utama (2007)12511EU921418IndonesiaDNone421S, 122L, 130P, 274K
  21EU921419IndonesiaDNone521S, 53K, 122L, 130S, 263E
Zaaijer (2007)5711EU155893SpainDNone1321S, 39K, 119F, 122L, 129L, 130P, 131T, 135N, 143C, 256G, 259A, 266R, 278I
Borroto-Esoda (2008)241GQ486039GermanyDNone521S, 91I, 122L, 129L, 271D
  111GQ486046GreeceDNone1916T, 21S, 24ST, 54H, 91I, 117PS, 118DN, 122L, 128INT, 130P, 139KN, 142AITV, 145LM, 248N, 256S, 263E, 266R, 317A, 329T
  121GQ486047BulgariaDNone1121S, 38E, 53KN, 54H, 78CS, 122L, 130P, 213ST, 238HN, 256G, 263E
  161GQ486051ItalyDNone621S, 54D, 122L, 130P, 215HQ, 256CG
  331GQ486068GreeceDNone916T, 21S, 118NT, 122L, 130P, 248N, 263E, 266V, 267H
  381GQ486073PolandDNone1316IT, 21S, 38AE, 91IL, 122L, 130P, 135Y, 215*PQS, 248N, 256S, 263E, 266R, 278IV
  641GQ486099GreeceDNone1416T, 21S, 54HY, 91I, 122L, 130P, 131H, 164M, 213N, 248N, 263E, 267H, 271D, 317AS
  671GQ486102GreeceDNone169N, 21S, 38E, 53K, 76D, 122L, 130P, 211T, 214AV, 238H, 245H, 248Q, 263E, 266R, 267H, 332CR
  1011GQ486136GermanyDNone167G, 21S, 53DN, 54H, 68A, 122L, 128NT, 130PS, 215H, 219A, 221S, 248N, 257H, 263E, 266V, 332Y
  1031GQ486138ItalyDNone1221S, 53K, 54D, 76D, 122L, 128NT, 130P, 142EV, 213ST, 248N, 263E, 267L
  1691GQ486204AustraliaDNone521S, 122L, 130P, 263E, 267H
  1791GQ486214PolandDNone137AV, 21S, 91IL, 122L, 123KN, 130PQ, 135SY, 213ST, 255EG, 263E, 271DE, 278IV, 329AT
  1861GQ486221GreeceDNone1321S, 53DN, 54H, 122L, 130P, 219A, 221FS, 248N, 256S, 263DE, 266KR, 271DE, 336M
  2151GQ486250FranceDNone1021S, 38E, 122L, 130P, 164M, 256G, 263E, 271D, 322S, 332CY
  2221GQ486257GermanyDNone1321S, 53DN, 109P, 112AV, 115LV, 122L, 130P, 149K, 214EV, 248N, 256CG, 263E, 266IV
  2251GQ486260BulgariaDNone1121S, 76DN, 122L, 130P, 213NT, 214AV, 248N, 256S, 263E, 266IR, 271D
  2481GQ486283BulgariaDNone119Y, 21S, 78C, 122L, 128S, 130P, 215S, 248N, 263E, 267H, 271D
  2621GQ486297FranceDNone821S, 54H, 110G, 122L, 128IT, 163IV, 263E, 266R
  2631GQ486298FranceDNone816IT, 21S, 53KN, 54DY, 122L, 130P, 248N, 263E
  2871GQ486322SpainDNone189HY, 21S, 53D, 54H, 76DN, 113AT, 122L, 130P, 142EV, 213T, 214AV, 238H, 245HY, 248N, 256S, 263E, 266V, 267H
  2881GQ486323GermanyDNone1618RS, 21S, 54H, 91IL, 122L, 130P, 213T, 214E, 238NS, 248N, 256G, 263E, 271D, 278C, 290IL, 336M
  2971GQ486332ItalyDNone1021S, 76D, 118DN, 122L, 130P, 215S, 238HN, 248N, 263E, 267L
  3031GQ486338PolandDNone1118RT, 21S, 38AE, 122L, 149KQ, 219A, 221Y, 248N, 256CS, 263E, 271D
  3041GQ486339USADNone821S, 122L, 128N, 130P, 215S, 248N, 263E, 267H
  3091GQ486344GermanyDNone1121S, 54HY, 76D, 91I, 122L, 130P, 187L, 248N, 263E, 266R, 271D
  3391GQ486374GermanyDNone1021S, 54H, 110G, 122L, 124N, 130P, 135Y, 238HN, 266R, 278I
  3701GQ486405GermanyDNone421S, 122L, 125K, 130P
  3941GQ486429BulgariaDNone147AS, 9HN, 21S, 106A, 122L, 128I, 130P, 142D, 219AS, 221FY, 248N, 256S, 263E, 336LM
  4511GQ486486CanadaDNone821S, 122L, 130P, 135Y, 233V, 248N, 256S, 263E
  4721GQ486507Czech RepublicDNone117V, 21S, 80IL, 91I, 130P, 135Y, 213ST, 248N, 263A, 266V, 278I
  4821GQ486517GermanyDNone1116IT, 21S, 38AE, 122L, 123NS, 130PS, 138KR, 142E, 221Y, 266IV, 332Y
  5111GQ486546CanadaDNone621S, 38E, 54HY, 122L, 248N, 266T
  5511GQ486586PolandDNone921S, 115V, 122L, 130P, 248N, 263E, 266V, 271D, 278I
  7341GQ486769GermanyDNone1618RS, 21S, 54H, 91I, 115LV, 118NT, 122L, 128AT, 130P, 142AV, 248N, 256G, 263E, 266V, 332Y, 333KQ
  7761GQ486811TurkeyDNone87D, 21S, 122L, 130P, 135Y, 181ST, 213ST, 266KR
  8231GQ486858TurkeyDNone1121S, 118D, 122L, 130P, 142AV, 164M, 187L, 219A, 263E, 266R, 271D
  8311GQ486866TurkeyDNone621S, 91I, 117P, 130P, 164M, 213T
Utsumi (2009)87191AB493845IndonesiaDNone821S, 78T, 116P, 122L, 124P, 130P, 163V, 215S
  201AB493846IndonesiaDNone513Y, 21S, 122L, 130P, 263E
  221AB493848IndonesiaDNone621S, 122L, 124P, 130P, 163V, 215S
Mulyanto (2010)2983TRF08226AB554016IndonesiaDNone521S, 122L, 130P, 212Q, 274K
  10GRS08457AB554023IndonesiaDNone521S, 122L, 130P, 274K, 325T
  11GRS08538AB554024IndonesiaDNone721S, 122L, 130P, 184A, 263E, 274K, 325T
Pourkarim (2010)27828C51FJ349232BelgiumDNone821S, 54H, 122L, 130P, 135F, 248N, 263E, 317Y
PowerJP (2010)3051PROGU570523UKDNone921S, 23I, 122L, 124N, 128I, 130P, 135Y, 138K, 142E
  2IPAT1 UKDNone721S, 54H, 122L, 124N, 130P, 135Y, 219A
Santos (2010)288637_HBVpv_1300HM101101BrazilDNone1121S, 53K, 54N, 122L, 128N, 130P, 238T, 248N, 263E, 317T, 332S
  1303_HBVpv_1300HM101108BrazilDNone921S, 122L, 124N, 130P, 131D, 135Y, 248N, 263E, 278I
  1441_HBVpv_1300HM101109BrazilDNone521S, 122L, 130P, 248N, 263E
  1539_HBVpv_1300HM101110BrazilDNone1221S, 110G, 122L, 129L, 130P, 248N, 263E, 266V, 267H, 271D, 278I, 336M
  1609_HBVpv_1300HM101111BrazilDNone1316T, 21S, 122L, 128I, 130P, 164M, 238H, 248N, 256S, 263E, 266V, 267H, 271D
  1728_HBVpv_1300HM101112BrazilDNone1316T, 21S, 122L, 128I, 130P, 164M, 238H, 248N, 256S, 263E, 266V, 267H, 271D
  3205_HBVpv_1300HM101127BrazilDNone916T, 21S, 122L, 130P, 131H, 248N, 263E, 266V, 278I
  3306_HBVpv_1300HM101128BrazilDNone921S, 122L, 124N, 130P, 131D, 135Y, 248N, 263E, 278I
Arankalle (2011)30931MOD_4605GQ183478IndiaDNone621S, 54H, 122L, 248N, 263E, 266T
  38MOD_4599GQ183485IndiaDNone1021S, 41*, 53D, 54H, 126R, 135Y, 248N, 263E, 266T, 271D
  39MOD_4568GQ183486IndiaDNone521S, 122L, 248N, 263E, 266K
Zhou (2011)31321GSD-8HM750151ChinaDNone521S, 115V, 122L, 248N, 263E

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