Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

HIV Home HBVseq HBV RT Mutations Blast Hits DB Release Notes

Query by HBV gp1 RT Mutation

Mutation 278I
Treatment L-Nucleoside analogs and/or ETV + ANPs (acyclic nucleoside phosphoates)
Genotype All
IncludeMixtures No
References 3
Patients 17

AuthorRefIDPtIsolateAccessionCountryGenotypeRxReceivedNumMutsMutList
Sheldon (2005)8112DQ132391GermanyD3TC,TDF754S, 55A, 122L, 130P, 135Y, 263E, 278I
  312DQ132412SpainD3TC,TDF5122L, 130P, 135Y, 263E, 278I
  322DQ132414SpainD3TC,TDF4122L, 130P, 135Y, 278I
  431DQ132430GermanyD3TC,TDF7122L, 130P, 135Y, 248N, 256S, 263E, 278I
Moriconi (2006)27412mDQ995843ItalyD3TC,ADV103GW, 9Y, 80I, 126R, 135Y, 180M, 204I, 248N, 261X, 278I
  424mDQ995844ItalyD3TC,ADV93GW, 9Y, 80I, 126R, 135Y, 180M, 204I, 248N, 278I
  1224mDQ995850ItalyD3TC,ADV1054H, 110GR, 118D, 126R, 135Y, 180M, 184S, 204V, 248N, 278I
  2724MDQ995860ItalyD3TC,ADV1716T, 21S, 78T, 122L, 128I, 130P, 142E, 151Y, 180M, 184S, 204I, 213ST, 221Y, 248N, 263E, 266V, 278I
Borroto-Esoda (2008)26351GQ486670GermanyD3TC,ADV3124Y, 266R, 278I
  6431GQ486678SpainD3TC,ADV821S, 26E, 122L, 130P, 131H, 263E, 267H, 278I
  6511GQ486686GermanyA3TC,ADV67E, 53T, 122H, 129L, 153QR, 278I
  6601GQ486695GermanyC3TC,ADV69Y, 11D, 91L, 181T, 269L, 278I
  6801GQ486715GermanyD3TC,ADV2124Y, 278I
  6831GQ486718GermanyA3TC,ADV657P, 122H, 129L, 246T, 278I, 337T
  6891GQ486724USAC3TC,ADV89NY, 13H, 223A, 224V, 238A, 267H, 278I, 317A
  6911GQ486726FranceD3TC,ADV821S, 76DN, 78T, 122L, 130P, 135Y, 263E, 278I
  7081GQ486743FranceC3TC,ADV129Y, 13H, 91L, 109S, 134DE, 223A, 224V, 238T, 267H, 278I, 317A, 337T
  8341GQ486869CanadaC3TC,ADV99Y, 13H, 91L, 164F, 221FY, 223A, 267Q, 278I, 317A

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