Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

HIV Home HBVseq HBV RT Mutations Blast Hits DB Release Notes

Query by HBV gp1 RT Mutation

Mutation 135Y
Treatment NumN(t)RTIs = 0
Genotype All
IncludeMixtures No
References 45
Patients 194

AuthorRefIDPtIsolateAccessionCountryGenotypeRxReceivedNumMutsMutList
Petzold (1986)25211AJ131956GermanyDNone1016T, 21S, 112I, 122L, 130P, 135Y, 248N, 256S, 263E, 278I
Gunther (1991)15911AF043594GermanyDNone816T, 126R, 135Y, 149K, 215S, 248N, 318R, 333Q
  11AF043594GermanyDNone816T, 126R, 135Y, 149K, 215S, 248N, 318R, 333Q
Preisler-Adams (1993)18211X72702GermanyDNone97T, 54H, 97S, 106T, 115V, 126R, 135Y, 256S, 278I
Plucienniczak (1994)17711Z35716PolandDNone5124N, 126R, 135Y, 248N, 309K
Duong (1995)12311AB090268JapanDNone553D, 54P, 126R, 135Y, 248N
  21AB090269JapanDNone653D, 54H, 122S, 126R, 135Y, 248N
  31AB090270JapanDNone454T, 126R, 135Y, 248N
Karayiannis (1995)11821X80925UKDNone1016L, 54H, 91I, 122L, 126R, 135Y, 202T, 248N, 317A, 329V
Alexopoulou (1996)13421X97849UKDNone854H, 91I, 122L, 126R, 135Y, 248N, 317A, 329V
Michitaka (1997)3311AB109475JapanDNone453D, 54H, 126R, 135Y
  21AB109476JapanDNone553D, 54H, 126R, 135Y, 248N
  31AB109477JapanDNone653D, 54H, 126R, 135Y, 248N, 337T
  141AB120308JapanDNone553D, 54P, 126R, 135Y, 248N
Rao (1997)17911U95551USADNone521S, 122L, 130P, 135Y, 278I
Garfein (1998)6311AY902768USADNone821S, 54H, 122L, 130P, 135Y, 164M, 215H, 271D
  21AY902769USADNone1121S, 54H, 122L, 130P, 135Y, 164M, 215H, 248N, 256S, 263E, 271D
  31AY902770USADNone1121S, 54H, 122L, 130P, 135Y, 164M, 215H, 248N, 256S, 263E, 271D
  41AY902771USADNone1121S, 54H, 122L, 130P, 135Y, 164M, 215H, 248N, 256S, 263E, 271D
  51AY902772USADNone1121S, 54H, 122L, 130P, 135Y, 164M, 215H, 248N, 256S, 263E, 271D
  61AY902773USADNone1121S, 54H, 122L, 130P, 135Y, 164M, 215H, 248N, 256S, 263E, 271D
  71AY902774USADNone1121S, 54H, 122L, 130P, 135Y, 164M, 215H, 248N, 256S, 263E, 271D
  81AY902776USADNone1121S, 54H, 122L, 130P, 135Y, 164M, 215H, 248N, 256S, 263E, 271D
  91AY902777USADNone1221S, 54H, 122L, 130P, 135Y, 164M, 212N, 215H, 248N, 256S, 263E, 271D
Tallo (1998)11101EU594404EstoniaDNone738E, 126R, 135Y, 248N, 256GS, 263T, 318R
  111EU594405EstoniaDNone5126R, 135Y, 248N, 309K, 318R
  121EU594406EstoniaDNone77T, 122V, 126R, 135Y, 267L, 309K, 318R
  131EU594407EstoniaDNone5126R, 135Y, 248N, 309K, 318R
  141EU594408EstoniaDNone4126R, 135Y, 248N, 318R
  151EU594410EstoniaDNone5126R, 135Y, 248N, 309K, 318R
  161EU594414EstoniaDNone5126R, 135Y, 248N, 309K, 318R
  171EU594415RussiaDNone4126R, 135Y, 248N, 318R
  181EU594416EstoniaDNone107V, 16T, 123D, 126R, 135Y, 145M, 248N, 309K, 317A, 318R
  191EU594416RussiaDNone107V, 16T, 123D, 126R, 135Y, 145M, 248N, 309K, 317A, 318R
  201EU594418RussiaDNone5126R, 135Y, 238H, 248N, 318R
  211EU594422RussiaDNone5126R, 131D, 135Y, 248N, 318R
  221EU594424RussiaDNone5126R, 135Y, 248N, 263A, 318R
  231EU594425RussiaDNone579CW, 126R, 135Y, 248N, 318R
  241EU594426RussiaDNone6126R, 135Y, 248N, 266K, 270T, 318R
  251EU594427RussiaDNone5126R, 135Y, 248N, 309K, 318R
  261EU594428KazakhstanDNone5126R, 131D, 135Y, 248N, 318R
  271EU594430RussiaDNone4126R, 135Y, 248N, 318R
  281EU594431EstoniaDNone87V, 16T, 126R, 135Y, 145M, 248N, 309K, 318R
  291EU594431RussiaDNone87V, 16T, 126R, 135Y, 145M, 248N, 309K, 318R
  301EU594432EstoniaDNone716T, 126R, 135Y, 145M, 248N, 309K, 318R
  311EU594432RussiaDNone716T, 126R, 135Y, 145M, 248N, 309K, 318R
  321EU594433RussiaDNone5126R, 128N, 135Y, 248N, 318R
Weinberger (1998)631AF065112GermanyDNone816T, 21S, 115V, 122L, 130P, 135Y, 148S, 193G
  81AF065117GermanyDNone538T, 54H, 119F, 126R, 135Y
  91AF065118GermanyDNone621S, 122V, 130P, 135Y, 151Y, 222S
  101AF065119GermanyDNone554H, 126R, 135Y, 187L, 215P
Jeantet (2001)20221AJ344117FranceDNone821S, 122L, 130P, 135Y, 248N, 256S, 263E, 278I
Sugauchi (2001)13101AB073830ThailandBNone530I, 124N, 135Y, 222T, 256C
Arauz-Ruiz (2002)1211AY090452SpainDNone738E, 54H, 118D, 122L, 135Y, 318R, 332Y
  21AY090453SwedenDNone916T, 53D, 54H, 126R, 131D, 135Y, 164M, 248N, 309K
Bracho (2002)23111AJ627215SpainDNone10109P, 115V, 126R, 135Y, 149K, 229M, 248N, 256S, 271D, 325L
Chen (2002)1011AB078031JapanDNone653D, 54H, 126R, 135Y, 287W, 290N
  21AB078032JapanDNone753D, 54H, 122V, 126R, 135Y, 248N, 287W
  31AB078033JapanDNone653D, 54H, 126R, 135Y, 248N, 287W
Alexopoulou (2003)21611AY341335GreeceDNone1054H, 126R, 130H, 131K, 135Y, 142A, 153Q, 164M, 317A, 329V
Bozdayi (2004)107101AY796031TurkeyDNone1016T, 54H, 91I, 135Y, 139D, 219A, 248N, 266K, 313S, 317A
Laoi (2004)9851EU159677IrelandDNone338S, 126R, 135Y
Avazova (2005)9941AB222710UzbekistanDNone4124Y, 135Y, 256S, 309K
Banerjee (2005)311DQ315776IndiaDNone621S, 122L, 124N, 130P, 135Y, 278I
  41DQ315779IndiaDNone157T, 76S, 123D, 130P, 131H, 135Y, 145M, 255D, 257W, 263E, 267H, 269L, 317A, 319R, 336M
  51DQ315780IndiaDNone87T, 123D, 135Y, 142E, 257W, 267H, 269L, 336M
Michitaka (2005)8211AB210819JapanDNone421S, 122L, 135Y, 278I
  21AB210820JapanDNone107T, 110G, 126R, 135Y, 137T, 248N, 257H, 266R, 318R, 329T
  31AB210822JapanDNone553D, 54H, 126R, 135Y, 248N
Nakajima (2005)13191AB205126JapanDNone453D, 54H, 126R, 135Y
 72101AB205127RussiaDNone628S, 126R, 135Y, 248N, 271D, 317A
Olinger (2005)15111EU414114BelarusDNone1438AT, 53E, 54R, 109P, 110GR, 126R, 135Y, 194AT, 215S, 237PT, 238D, 248N, 256S, 257W
  121EU414115BelarusDNone754H, 126HR, 135Y, 213T, 248N, 256S, 257W
  131EU414116BelarusDNone5134N, 135Y, 248N, 256S, 257W
  141EU414117BelarusDNone7118D, 126R, 131D, 135Y, 248N, 256S, 257W
  151EU414118BelarusDNone938E, 76D, 91I, 115M, 126R, 131D, 135Y, 256S, 257W
  161EU414120BelarusDNone6126R, 129I, 135Y, 248N, 256S, 257W
  171EU414121BelarusDNone87D, 54H, 126R, 132M, 135Y, 248N, 256S, 257W
  181EU414122BelarusDNone6126R, 135Y, 248N, 253I, 256S, 257W
  191EU414123BelarusDNone654H, 126R, 135Y, 248N, 256S, 257W
  201EU414124BelarusDNone5126R, 135Y, 248N, 256S, 257W
  211EU414125BelarusDNone6118D, 126R, 135Y, 248N, 256S, 257W
  221EU414126BelarusDNone654H, 126R, 135Y, 248N, 256S, 257W
  231EU414128BelarusDNone6126R, 135Y, 145M, 238H, 256S, 257W
  241EU414130BelarusDNone6126R, 135Y, 149K, 248N, 256S, 257W
  311EU414138BelarusDNone8126R, 135Y, 149K, 248N, 256CS, 257*CWY, 266V, 318R
  321EU414139BelarusDNone654H, 126R, 135Y, 248N, 256CS, 257*CWY
Andernach (2006)2141FJ692505HaitiDNone621S, 122L, 130P, 135Y, 154Q, 248N
  51FJ692506HaitiDNone521S, 122L, 130P, 135Y, 248N
  61FJ692507HaitiDNone521S, 122L, 130P, 135Y, 248N
Garmiri (2006)2651GQ161757GuineaENone415K, 135Y, 162V, 238T
Grabarczyk (2006)3411GQ477452PolandDNone6118D, 126R, 135Y, 215P, 309K, 318R
  21GQ477453PolandDNone1076D, 123H, 126R, 135Y, 163V, 173M, 219A, 245H, 248N, 318R
  31GQ477454PolandDNone935Q, 118D, 122V, 128N, 135Y, 181S, 185T, 248N, 271D
  41GQ477455PolandDNone854H, 126R, 135Y, 145M, 215S, 238H, 248N, 329T
  51GQ477456PolandDNone67T, 126R, 135Y, 213T, 248N, 318R
  61GQ477457PolandDNone554H, 126R, 135Y, 248N, 329T
Khan (2006)11341AB330369TajikistanDNone3109P, 135Y, 318R
Mrani (2007)17411AM422939FranceDNone88Q, 21S, 122L, 130P, 131D, 135Y, 263E, 278I
Okamoto (2007)10941AB033558JapanDNone6123D, 135Y, 267H, 269L, 332Y, 336M
Pallier (2007)161 FranceDNone1191I, 110G, 115M, 126R, 135Y, 215S, 229G, 238E, 248N, 253S, 271D
Tallo (2007)11991EU594399RussiaDNone5126R, 135Y, 248N, 271D, 318R
  101EU594400EstoniaDNone5126R, 135Y, 248N, 309K, 318R
  111EU594401EstoniaDNone716T, 126R, 135Y, 145M, 248N, 309K, 318R
  121EU594402RussiaDNone716T, 126R, 135Y, 145M, 248N, 309K, 318R
  131EU594403EstoniaDNone5126R, 135Y, 248N, 309K, 318R
  141EU594409EstoniaDNone716T, 126R, 135Y, 145M, 248N, 309K, 318R
  151EU594411EstoniaDNone5115M, 126R, 135Y, 248N, 318R
  161EU594412EstoniaDNone5115M, 126R, 135Y, 248N, 318R
  171EU594413EstoniaDNone5126R, 135Y, 248N, 309K, 318R
  181EU594417RussiaDNone716T, 126R, 135Y, 145M, 248N, 309K, 318R
  191EU594419RussiaDNone5126R, 131D, 135Y, 248N, 318R
  201EU594420RussiaDNone5126R, 131D, 135Y, 248N, 318R
  211EU594421RussiaDNone4126R, 135Y, 248N, 318R
  221EU594423RussiaDNone5126R, 131D, 135Y, 248N, 318R
  231EU594429RussiaDNone87V, 16T, 126R, 135Y, 145M, 248N, 309K, 318R
Borroto-Esoda (2008)261GQ486041GreeceDNone753D, 54H, 126R, 128NT, 135Y, 266R, 271D
  321GQ486067GermanyDNone691IL, 126R, 135Y, 248N, 266R, 318R
  361GQ486071BulgariaDNone654H, 106ST, 115V, 126R, 135Y, 266K
  381GQ486073PolandDNone1316IT, 21S, 38AE, 91IL, 122L, 130P, 135Y, 215*PQS, 248N, 256S, 263E, 266R, 278IV
  511GQ486086GreeceDNone147T, 23I, 54H, 76D, 115V, 117PS, 120GR, 126R, 135Y, 215HQ, 221FY, 256G, 266R, 278I
  781GQ486113GreeceDNone954H, 106T, 109P, 110G, 115V, 126R, 135Y, 215S, 278I
  901GQ486125SpainDNone1254H, 91I, 126R, 135Y, 138RS, 212KT, 214A, 248N, 266IKR, 318R, 333KQ, 338F
  1021GQ486137SpainDNone107V, 54HY, 126R, 135Y, 219A, 233V, 248N, 257HY, 271A, 318R
  1221GQ486157GermanyDNone1121T, 38E, 53DE, 54HY, 91IL, 118D, 122I, 126R, 135Y, 309K, 318R
  1311GQ486166CanadaDNone554H, 126R, 135Y, 139KN, 215P
  1421GQ486177GreeceDNone187T, 53S, 54H, 76D, 91I, 117HPSY, 118DN, 120G, 122V, 126R, 135Y, 215S, 248N, 256S, 266R, 267HL, 271D, 309KM
  1461GQ486181AustraliaDNone1138S, 53D, 54H, 126R, 135Y, 139KN, 215*PQS, 220IL, 248N, 257HY, 266IK
  1641GQ486199SpainDNone954H, 118T, 123E, 135Y, 228FL, 263E, 271D, 318R, 337T
  1651GQ486200SpainDNone754H, 91I, 126R, 135Y, 248N, 318R, 337T
  1801GQ486215GreeceDNone1038E, 54H, 106T, 110G, 115V, 126R, 135Y, 142G, 143T, 278I
  1961GQ486231BulgariaDNone854N, 123KN, 135Y, 139D, 149KQ, 163V, 229LM, 256S
  2001GQ486235GreeceDNone454H, 110GR, 126R, 135Y
  2271GQ486262PolandDNone654H, 118D, 126R, 135Y, 248N, 329T
  2511GQ486286GermanyDNone87AD, 54H, 106AT, 115V, 126R, 135Y, 235I, 278I
  2541GQ486289GreeceDNone654H, 106A, 115V, 126HR, 135Y, 256CG
  2591GQ486294GermanyDNone754HY, 110GR, 118D, 126R, 135Y, 271D, 309K
  2671GQ486302PolandDNone813L, 126R, 131D, 135Y, 238H, 248N, 318R, 332Y
  2731GQ486308Czech RepublicDNone1154H, 76D, 110G, 118NT, 122V, 135Y, 199LV, 213T, 220LV, 233V, 266R
  2901GQ486325SpainDNone1316IT, 18RST, 54H, 91I, 110G, 135Y, 215*PQS, 234HN, 248N, 253S, 266R, 271D, 318R
  3221GQ486357CanadaDNone754H, 109PS, 117PS, 126HR, 135Y, 248N, 270R
  3391GQ486374GermanyDNone1021S, 54H, 110G, 122L, 124N, 130P, 135Y, 238HN, 266R, 278I
  3461GQ486381BulgariaDNone854H, 106A, 115V, 126R, 135Y, 215P, 278IT, 309K
  4381GQ486473PolandDNone6126HR, 135Y, 248N, 271D, 309L, 337HN
  4511GQ486486CanadaDNone821S, 122L, 130P, 135Y, 233V, 248N, 256S, 263E
  4531GQ486488PolandDNone57T, 126R, 135Y, 248N, 318R
  4541GQ486489FranceDNone654H, 122L, 126R, 128NT, 135Y, 248N
  4721GQ486507Czech RepublicDNone117V, 21S, 80IL, 91I, 130P, 135Y, 213ST, 248N, 263A, 266V, 278I
  4901GQ486525PolandDNone1054H, 78ST, 113AG, 126R, 135Y, 214A, 215R, 246H, 266IR, 271DN
  4951GQ486530Czech RepublicDNone6118D, 121S, 123KN, 126R, 135Y, 271D
  5791GQ486614CanadaDNone653D, 54H, 78ST, 126R, 135Y, 271D
  5991GQ486634BulgariaDNone854H, 106T, 115V, 126R, 128NT, 135Y, 219AS, 278I
  6001GQ486635BulgariaDNone854H, 106T, 115V, 126R, 135Y, 213ST, 267H, 278I
  7461GQ486781TurkeyDNone838K, 54H, 110G, 123DN, 126R, 135Y, 215H, 229LM
  7501GQ486785SpainDNone1254H, 91I, 122V, 126L, 135Y, 253S, 271D, 316H, 318R, 332R, 333N, 337T
  7651GQ486800CanadaCNone8109PQ, 134DG, 135Y, 139KN, 153CW, 214AV, 238D, 256C
  7761GQ486811TurkeyDNone87D, 21S, 122L, 130P, 135Y, 181ST, 213ST, 266KR
Li (2008)281091GQ377622ChinaBNone3124N, 135Y, 333Q
Meldal (2009)27065M20GQ924668MalaysiaBNone3124N, 135Y, 222T
  7M17GQ924609MalaysiaCNone69Y, 13H, 135Y, 269L, 278I, 325S
  11M31GQ924614MalaysiaCNone89Y, 13H, 91L, 135Y, 267Q, 269L, 278I, 317A
  49M89GQ924652MalaysiaDNone553D, 54H, 126R, 135Y, 266R
DupinayT (2010)2993900-02FN821458MadagascarDNone2126R, 135Y
GhoshS (2010)2931T1178GQ205377IndiaDNone854H, 123D, 135Y, 267H, 269L, 317A, 326P, 336M
  2T1181GQ205378IndiaDNone117T, 54H, 123D, 135Y, 257W, 263E, 267H, 269L, 317A, 326P, 336M
  3T1234GQ205379IndiaDNone107T, 76S, 123D, 135Y, 215H, 257W, 263E, 267H, 269L, 336M
  5T1360aGQ205381IndiaDNone117T, 76S, 123D, 135Y, 256S, 257W, 263E, 267H, 269L, 317A, 336M
  5T1360dGQ205382IndiaDNone107T, 76S, 123D, 135Y, 257W, 263E, 267H, 269L, 317A, 336M
  6T1434bGQ205383IndiaDNone117T, 76S, 123D, 135Y, 208I, 257W, 263E, 267H, 269L, 317A, 336M
  6T1434dGQ205384IndiaDNone107T, 76G, 123D, 135Y, 257W, 263E, 267H, 269L, 317A, 336M
  7T1469GQ205385IndiaDNone127T, 54H, 119F, 123D, 135Y, 257W, 263E, 267H, 269L, 317A, 326P, 336M
  8T1503GQ205386IndiaDNone117T, 54H, 123D, 135Y, 257W, 263E, 267H, 269L, 317A, 326P, 336M
  9T1545GQ205387IndiaDNone127T, 54H, 123D, 135Y, 257W, 263E, 267H, 269L, 317A, 326P, 329T, 336M
  10T1562GQ205388IndiaDNone117T, 54H, 123D, 135Y, 257W, 263E, 267H, 269L, 317A, 326P, 336M
  11T1667GQ205389IndiaDNone117T, 54H, 123D, 135Y, 257W, 263E, 267H, 269L, 317A, 326P, 336M
Nguye (2010)271435P8318222HM173992USABNone2134D, 135Y
  678P6921722HM174067USACNone1135Y
PowerJP (2010)3051PROGU570523UKDNone921S, 23I, 122L, 124N, 128I, 130P, 135Y, 138K, 142E
  2IPAT1 UKDNone721S, 54H, 122L, 124N, 130P, 135Y, 219A
Santos (2010)288714_HBVpv_1300HM101102BrazilDNone6135Y, 149K, 153W, 248N, 257W, 267L
  1303_HBVpv_1300HM101108BrazilDNone921S, 122L, 124N, 130P, 131D, 135Y, 248N, 263E, 278I
  3306_HBVpv_1300HM101128BrazilDNone921S, 122L, 124N, 130P, 131D, 135Y, 248N, 263E, 278I
Verheye (2010)272149149_250307HM174192GermanyDNone1135Y
  246246_020608HM174232GermanyDNone4122L, 130P, 132M, 135Y
  265265_120908HM174239GermanyDNone7122FL, 126HR, 130PQ, 132LM, 135Y, 219AS, 229LM
Arankalle (2011)30927MOD_4594GQ183474IndiaDNone854H, 126R, 135Y, 139S, 219A, 248N, 279D, 291G
  28MOD_4575GQ183475IndiaDNone653D, 54H, 126R, 135Y, 139S, 248N
  29MOD_4603GQ183476IndiaDNone653D, 54H, 126R, 135Y, 139S, 248N
  32MOD_4607GQ183479IndiaDNone753D, 54H, 84A, 126R, 135Y, 139S, 326I
  34MOD_4569GQ183481IndiaDNone553D, 54H, 135Y, 139S, 248N
  35MOD_4570GQ183482IndiaDNone738T, 53D, 54H, 126R, 135Y, 139S, 248N
  36MOD_4566GQ183483IndiaDNone653D, 54H, 126R, 135Y, 139S, 248N
  37MOD_4598GQ183484IndiaDNone853D, 54H, 126R, 135Y, 230T, 248N, 256S, 263N
  38MOD_4599GQ183485IndiaDNone1021S, 41*, 53D, 54H, 126R, 135Y, 248N, 263E, 266T, 271D
Pezzano (2011)2878BA124GU207487ArgentinaDNone4122L, 124N, 130P, 135Y
  41BA166HM154963ArgentinaDNone3122I, 130P, 135Y
  48BA173HM154970ArgentinaDNone3122L, 130P, 135Y

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