<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd"> HIVdb: Genotypic Resistance Interpretation Algorithm

HIVdb: Genotypic Resistance Interpretation Algorithm


SeqID:    Date: 12-May-2006

The Team

The Data

Mutation Scoring
240 380
Sequence Quality Assessment
Gene QA Problem Codons
PR Stop Codons, Frame Shifts:
PR B,D,H,V,N:
PR Unusual Residues:
Gene QA Problem Codons
RT Stop Codons, Frame Shifts:
RT B,D,H,V,N:
RT Unusual Residues:
    Blue lines indicate differences from consensus B; tall blue lines indicate sites associated with drug resistance.
    Red lines indicate QA problems.


Summary Data
Sequence includes PR: codons: -
Sequence includes RT: codons: -
There are no insertions or deletions
Subtype and % similarity to closest reference isolate:
  1. PR: (%)
  2. RT: (%)
   AA Insertion:  codon      AA:      NA:
  1. Shift of length nucleic acids at codon in

  2. 					
    				
Drug Resistance Interpretation
PI Major Resistance Mutations:
PI Minor Resistance Mutations:
PR Other Mutations:

10
Protease Inhibitors
PR Comments

Drug Resistance Interpretation
NRTI Resistance Mutations:
NNRTI Resistance Mutations:
RT Other Mutations:

20
Nucleoside RTI
10
Non-Nucleoside RTI
RT Comments
There is a reading frame shift! Please examine the sequence carefully. The presence of a reading frame shift (insertions or deletions that are not multiples of 3 NA) suggests the possibility of a sequencing error. Reading frame shifts in this sequence are shown below. A region of the underlying raw alignment text on either side of the reading frame shift is also shown.
  1. Shift of length nucleic acids at codon in

  2. 					
    				
None , % %
Susceptible Potential low-level resistance Low-level resistance Intermediate resistance High-level resistance
 
 
Total:
http://hivdb.stanford.edu/cgi-bin/GetResiData.cgi?pos= &drug= &class= &drug1=any