Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

PI Resistance Notes

Last updated on Feb 28, 2014
Position
 
ConsAAFPV/r
 
IDV/r
 
NFV
 
SQV/r
 
LPV/r
 
ATV/r
 
TPV/r
 
DRV/r
 
50IL-5-5-5-5-1060-5-10
10LI00000000
10LR00000000
10LV00000000
10LY00000000
11VI50000005
11VL50000005
13IV00000000
20KM00000000
20KR00000000
33LV00000000
33LI00000000
36MI00000000
36ML00000000
36MV00000000
36MT00000000
43KT000000100
53FL0001501000
53FY00000000
63LP00000000
71AT00000000
71AV00000000
76LV60300-530-5-520
77VI00000000
82VI00000000
85IV00000000
89LI00000000
89LM00000000
89LT00000000
93IL00000000
20KV00500000
24LF55555500
24LM55555500
33LF1005055105
35EG00500050
58QE005005150
71AI50550500
71AL50550500
73GV55555500
89LV55500005
10LF10101005005
20KI001000000
20KT551000500
24LI101010101010-50
82VL151010101010450
82VC101010101010100
83ND0101010010200
23LI001500000
32VI30151501515515
47IV30151501553010
50IV6001515300-520
73GC510151551000
73GS510151551000
73GT510151551000
73GA510151551000
74TP10101510510205
74TS001500000
46MI1010205101050
46ML10102051010100
46MV101020551050
54IL601020151515-1020
54IM6015201515152020
54IS101520151015200
54IT101520151015200
54IV101520151515200
54IA101520151015200
47IA60153006053010
48GV0103060103000
48GM0103060103000
48GA0103060101000
48GS0103060101000
48GT0103060101000
48GQ0103060101000
48GL0103060101000
82VA15303015301500
82VF303030103015015
82VS103030102525250
82VT103030102525450
82VM103030102510100
88ND003050500
88NT0030001500
88NG0030001500
30DN006000000
84IA6060606060606030
84IV6060606030603015
84IC6060606030603010
88NS-101560150600-5
90LM20306040152500

There are 46 combination rules below conditional on several mutations.
If triggered, their scores are added to the total score from the individual mutations above.
Drug NameCombination RuleScore
ATV/r46ILV+82ATSFMCL10
ATV/r46ILV+90M10
ATV/r53L+90M10
ATV/r54AVSTLM+82ATSFMCL10
ATV/r73STCA+90M10
ATV/r82ATSFMCL+90M10
DRV/r32I+47VA5
DRV/r32I+54ML10
DRV/r47VA+54ML5
FPV/r10F+82ATSLCM10
FPV/r32I+82ATSLCM10
FPV/r33F+82ATSLCM10
FPV/r46ILV+82ATSLCM10
FPV/r47V+82ATSLCM10
FPV/r54AVST+82ATSLCM10
FPV/r89V+82ATSLCM10
IDV/r24IFM+82ATSFMCL10
IDV/r32I+47VA15
IDV/r32I+54M15
IDV/r46IL+76V10
IDV/r46ILV+82ATSFMCL10
IDV/r46ILV+90M10
IDV/r47VA+54M15
IDV/r54AVSTLM+82ATSFMC10
IDV/r73STCA+90M10
LPV/r32I+47V10
LPV/r32I+54ML10
LPV/r46IL+76V10
LPV/r46ILV+82AFSTMC5
LPV/r47V+54ML10
LPV/r54VSTAML+82AFSTMC10
LPV/r82AFSTMC+24IFM10
LPV/r90M+82AFSTMC5
LPV/r90M+84V5
NFV46IL+76V10
NFV46ILV+82AFSTMC10
NFV54VSTAML+82AFSTMC10
SQV/r53L+90M10
SQV/r54AVSTLM+82ATSFMC10
SQV/r54AVSTLM+90M5
SQV/r73STCA+90M10
SQV/r82ATSFMC+90M10
TPV/r74P+47VA10
TPV/r74P+84VC10
TPV/r83D+47VA10
TPV/r83D+84VC10