## PI Resistance Notes

Last updated on Feb 28, 2014

Resistance Matrix | Resistance Mutation Comments | Resistance Mutation Scores |

There are 46 combination rules below conditional on several mutations.

If triggered, their scores are added to the total score from the individual mutations above.

Drug Name | Combination Rule | Score |
---|---|---|

ATV/r | 46ILV+82ATSFMCL | 10 |

ATV/r | 46ILV+90M | 10 |

ATV/r | 53L+90M | 10 |

ATV/r | 54AVSTLM+82ATSFMCL | 10 |

ATV/r | 73STCA+90M | 10 |

ATV/r | 82ATSFMCL+90M | 10 |

DRV/r | 32I+47VA | 5 |

DRV/r | 32I+54ML | 10 |

DRV/r | 47VA+54ML | 5 |

FPV/r | 10F+82ATSLCM | 10 |

FPV/r | 32I+82ATSLCM | 10 |

FPV/r | 33F+82ATSLCM | 10 |

FPV/r | 46ILV+82ATSLCM | 10 |

FPV/r | 47V+82ATSLCM | 10 |

FPV/r | 54AVST+82ATSLCM | 10 |

FPV/r | 89V+82ATSLCM | 10 |

IDV/r | 24IFM+82ATSFMCL | 10 |

IDV/r | 32I+47VA | 15 |

IDV/r | 32I+54M | 15 |

IDV/r | 46IL+76V | 10 |

IDV/r | 46ILV+82ATSFMCL | 10 |

IDV/r | 46ILV+90M | 10 |

IDV/r | 47VA+54M | 15 |

IDV/r | 54AVSTLM+82ATSFMC | 10 |

IDV/r | 73STCA+90M | 10 |

LPV/r | 32I+47V | 10 |

LPV/r | 32I+54ML | 10 |

LPV/r | 46IL+76V | 10 |

LPV/r | 46ILV+82AFSTMC | 5 |

LPV/r | 47V+54ML | 10 |

LPV/r | 54VSTAML+82AFSTMC | 10 |

LPV/r | 82AFSTMC+24IFM | 10 |

LPV/r | 90M+82AFSTMC | 5 |

LPV/r | 90M+84V | 5 |

NFV | 46IL+76V | 10 |

NFV | 46ILV+82AFSTMC | 10 |

NFV | 54VSTAML+82AFSTMC | 10 |

SQV/r | 53L+90M | 10 |

SQV/r | 54AVSTLM+82ATSFMC | 10 |

SQV/r | 54AVSTLM+90M | 5 |

SQV/r | 73STCA+90M | 10 |

SQV/r | 82ATSFMC+90M | 10 |

TPV/r | 74P+47VA | 10 |

TPV/r | 74P+84VC | 10 |

TPV/r | 83D+47VA | 10 |

TPV/r | 83D+84VC | 10 |