Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

NNRTI Resistance Notes

Last updated on Feb 28, 2014
Position
 
ConsAAEFV
 
NVP
 
ETR
 
RPV
 
101KP60604560
103KN606000
103KS456000
103KT156000
103KH606000
106VA456000
106VM606000
181YC30603030
181YI30606060
181YV30606060
181YS15601515
181YF15603030
181YG15603030
188YC606000
188YH306000
188YL60601560
190GA45601515
190GS60601515
190GE60604545
190GQ60604545
190GC60601010
190GV60601010
190GT60601010
230ML45603045
238KT306000
100LI45453060
98AG10301015
100LV30301015
101KE15301530
188YF6030030
225PH303000
227FC30303030
227FL153000
230MI15301530
318YF103000
101KH15151010
108VI101500
179VF10151515
348NI101500
138EK10101030
138EQ10101015
138EG10101015
138ER10101015
179VD10101010
179VE10101010
179VT10101010
179VL10101015
221HY10101010
238KN101000
90VI0000
101KQ0000
101KN0000
103KR0000
103KQ0000
103KE0000
106VI0000
138EA001015
179VI0000
234LI0000
236PL0000

There are 10 combination rules below conditional on several mutations.
If triggered, their scores are added to the total score from the individual mutations above.
Drug NameCombination RuleScore
EFV103R+179DE20
EFV106A+227L15
ETR181C+179F15
ETR181C+190ASCVT10
NVP103R+179DE20
RPV101E+184I20
RPV103R+179D15
RPV138K+184I30
RPV181C+179F15
RPV181C+190ASCVT10