Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.
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Updated on Mar 4, 2014

Interactive Scores (IScores) applies genotypic scores to distinct HIV-1 RT and protease mutation patterns from ~40,000 individuals with group M sequences.
  • 'Show All Patterns & Levels': The complete list of all patterns and resistance levels (1 to 5).
  • 'Show Specific Patterns': The complete list of all patterns and resistance levels containing a specific mutation or mutation combination.

  • 'Score Changes' text box: To examine the effects of a score change enter changes in the following format (e.g. 'ABC:30, TDF:30').
  • 'Include' checkbox: Uncheck to assign all scores to 0.
  • 'Maximum Result Count': Limits the number of mutation patterns returned: It takes ~5 seconds to return 100 recalculated resistance levels.
PI Scores (HIVdb 6p3)
Algorithm           
      Maximum Result Count
IncludeMutationATVFPVIDVLPVNFVSQVTPVDRVScore Changes
10F05555005
10I00005000
10R00005000
10V00005050
10Y00005000
11I05000005
11L05000005
20I00005000
20M00005000
20T5555105500
20V000010000
23I000030000
24I55101055-50
24F55555500
30N000060000
32I15301515150515
33F510055055
35G00005050
43T000000100
46I1010101015050
46L1010101015050
46V555510000
47V03010151502010
47A56015603002010
IncludeMutationATVFPVIDVLPVNFVSQVTPVDRVScore Changes
48V3001010306000
48M3001010306000
48A3001010306000
48S3001010306000
48T3001010306000
48Q3001010306000
48L3001010306000
50V0600201010-1020
50L60-5-5-10-5-5-5-10
53L500501000
53Y00000500
54L15605201510-1015
54M1560102015102015
54S151015101515150
54T151015101515150
54V151015101515150
54A151015101515150
58E500050100
71T00005000
71V00005000
71I55555500
71L55555500
73C10555101005
73S10555101005
73T10555101005
IncludeMutationATVFPVIDVLPVNFVSQVTPVDRVScore Changes
73A10555101005
74P555555205
74S000010000
76V-106030300-10-1020
82A15103020301000
82F15303020300010
82S151030203010150
82T151030203010300
82M101015151010100
82L10101001010300
82C101010101010100
83D505055200
84A6060603060603020
84V3060301560603010
84C3030301560601510
88D505030500
88S60-101006050-5
88T1000030000
88G1000030000
89V05505005
90M20202010603000
00032I+47VA+54ML+33F00032I+47VA+54ML+33F
32I+47VA0010100000
32I+47VA+54ML00101000010
32I+47VA+54ML+10F00550005
IncludeMutationATVFPVIDVLPVNFVSQVTPVDRVScore Changes
32I+47VA+54ML+73STCA00550005
32I+47VA+54ML+74P00550005
32I+47VA+54ML+89V00550005
32I+47VA+54ML+90M0010100000
32I+54ML+84VA00101000010
32I+54ML+84VA+10F00550005
32I+54ML+84VA+33F00050005
32I+54ML+84VA+73STCA00550005
32I+54ML+84VA+89V00550005
32I+54ML+84VA+90M0010100000
46IL+76V0010100000
46ILV+82ATS05000000
46ILV+82ATS+10FIVRY05000000
46ILV+82ATS+71VTLI05000000
46ILV+82ATSC10010001000
46ILV+90M1000001000
53L+90M1000001000
54VASTLM+82ATS05000000
54VASTLM+82ATS+10FIVRY05000000
54VASTLM+82ATS+71VTLI05000000
54VATSML+82ATSC1000001000
54VATSML+90M1000001000
54VSTA+82ATSF+10F0010100000
54VSTA+82ATSF+10IVR00550000
54VSTA+82ATSF+24I0010100000
IncludeMutationATVFPVIDVLPVNFVSQVTPVDRVScore Changes
54VSTA+82ATSF+46ILV0010100000
54VSTA+82ATSF+90M0010100000
73STCA+90M10010001000
82ATSC+90M1000001000
84VAC+90M100101001000